TITLE

CELL CYCLE PHASE DISTRIBUTION IN NEOPLASTIC PROGRESSION OF BARRETT'S OESOPHAGUS

AUTHOR(S)
Lao-Sirieix, P.; Brais, R.; Coleman, N.; Fitzgerald, R.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA26
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
It has been demonstrated that there is an increased proliferation index as the Barrett's oesophagus (BE) mucosa progresses through the metaplasia-dysplasia-adenocarcinoma sequence. Understanding of the cell cycle phase distribution in BE could shed light on the basic abnormalities leading to uncontrolled proliferation and cancer progression. This article determines whether the increased proliferation associated with progression of Barrett's oesophagus could be attributed to abnormalities in cell cycle phase.
ACCESSION #
13218915

 

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