Selvasekar, C. R.; Thorpe, S.; Novelli, N.; Bown, S. G.; Lovar, L. B.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA25
Academic Journal
Previous studies suggest that when high grade dysplasia (HGD) is diagnosed within Barrett's oesophagus (BE), up to 50% of patients have invasive cancer so should be offered surgery. This article documents the true prevalence of cancer in patients referred to the National Medical Laser Centre to enter trials of photodynamic therapy (PDT). This study shows good agreement in the diagnosis of HGD among pathologists and demonstrates the huge interobserver variation in the diagnosis of low grade dysplasia in BE.


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