TITLE

H PYLORI INFECTION IN A CHINESE FISHING POPULATION: DOES HELMINTH INFECTION PROTECT AGAINST GASTRIC ATROPHY

AUTHOR(S)
Y. Q. Du; Agnew, A.; Ye, X. P.; Jeremy, A. H. T.; Crabtree, J. E.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA23
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on H pylori infection in a Chinese fishing population and analyses the role of helminth infection in protection against gastric atrophy. Murine studies have shown infection with enteric helminths modulates gastric Th1 responses to H pylori and protects against gastric atrophy. There is no clinical data on the effects of helminth co-infection on H pylori gastritis in humans. In subjects with both H pylori and S japonicum infection CagA seropositivity is reduced, which may reflect modulation of immune responses or strain selection.
ACCESSION #
13218904

 

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