Howarth, S. M.; Morgan, J. M.; Williams, G. T.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA21
Academic Journal
This article focuses on the new 6th edition TNM classification of colorectal cancer. The new 6th edition of the TNM staging classification of colorectal cancer changes the histological criteria for interpreting extramural tumour nodules. Changes to TNM staging in the 6th edition have replaced an objective criterion with one that is subjective and not reproducible by pathologists. Application of the new TNM classification "upstages" up to 11% of 13 colorectal cancers. This has implications for patient treatment, clinical trials and cancer intelligence.


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