Dalton, H. R.; Fellows, H. J.; Bendall, R.; Mitchell, J.; Banks, M.; Levine, D.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA14
Academic Journal
Hepatitis E is uncommon in the developed world and largely confined to people who have travelled to endemic areas. There have been several case reports of hepatitis E in patients who have not travelled to endemic areas and some evidence to support a zoonotic source of infection in such patients. The aim of this study is to identify the incidence of acute sporadic icteric hepatitis E in rural England. The incidence of sporadic icteric hepatitis E in Cornwall, England, is at least 0.25/100 000/year. Unlike endemic hepatitis E, it has a predilection for the middle aged and elderly in whom it is occasionally fatal. Viral sequencing suggests that sporadic hepatitis E may be a zoonosis from a pig reservoir.


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