TITLE

OPTICAL BIOPSY OF COLONIC LESIONS: COMPARISON OF ELASTIC SCATTERING SPECTROSCOPY WITH HISTOLOGY

AUTHOR(S)
Dhar, A.; Johnson, K. S.; Novelli, M. R.; Bown, S. G.; Lovat, L. B.; Bloom, S. L.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA9
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Diagnosis of colonic pathology requires conventional histology of multiple biopsies, which has a high sampling error and a low diagnostic yield. Elastic Scattering Spectroscopy (ESS) is a novel optical technique, which can distinguish between normal and abnormal tissue instantaneously in vivo. Authors present their initial results using thisnovel technology in the colon. Despite small data sets particularly for hyperplastic polyps, these data suggest that ESS may be capable of differentiating various colonic lesions in real time allowing an in vivo optical biopsy measurement. It may be valuable in targeting polypectomy and dysplasia surveillance in patients with chronic ulcerative colitis.
ACCESSION #
13218849

 

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