Hurlstone, D. P.; Cross, S. S.; Shorthouse, A. J.; Brown, S.; Adam, I.; Sanders, D. S.; Lobo, A. J.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA8
Academic Journal
High Magnification Chromoscopic Colonoscopy (HNPCC) is the most common of the hereditary colon cancer syndromes approximating to 1.5% of the colon cancer (CC) burden in Great Britain. HNPCC is associated with right sided CC. In addition to exophytic polyps, flat and depressed lesions occur which undergo an accelerated adenoma-carcinoma sequence in addition to de novo neoplastic transformation. Such lesions are difficult to detect using conventional colonoscopy. HMCC improves the detection of flat neoplastic lesions in HNPCC. Endoscopic screening in this "high risk" group may be enhanced using HMCC. Significantly more flat lesions were detected using HMCC conventional colonoscopy.


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