TITLE

NON-RESPONSIVE COELIAC DISEASE -- EXPRIENCE OF A TERTIARY REFERRAL CENTRE

AUTHOR(S)
Dewar, D. H.; Johnson, M.; Ellis, H. J.; Ciclitira, P. J.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA6
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Failure to respond to a gluten free diet, either clinically or histologically, defines non-responsive coeliac disease. Refractory coeliac disease is rare and describes persisting gluten induced enteropathy when other causes have been excluded. The prognosis is poor and there is a high incidence of enteropathy associated T cell lymphoma. Therefore, all patients with primary or secondary non-responsive coeliac disease should be extensively investigated. Authors conclude that continued gluten ingestion is still the predominant cause of non-response to dietary treatment in coeliac disease. Thorough assessment will identify a potentially treatable cause in the majority of patients.
ACCESSION #
13218837

 

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