TITLE

MALIGNANCY AND MORTALITY IN PEOPLE WITH COELIAC DIEASE: A GENRAL POPULATION BASED COHORT STUDY

AUTHOR(S)
J.West; Logan, R. F. A.; Smith, C.; Hubbard, R.; Card, T. R.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA6
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
People with coeliac disease may be at increased risk of gastrointestinal malignancy, lymphoma, and mortality, but at decreased risk of other cancers. Authors performed a population based cohort study using the General Practice Research Database to quantify the risks in people with coeliac disease compared with the general population. There were modest increases in the overall risks of malignancy and mortality in people with coeliac disease and most of this excess risk was in the first year of follow up alter diagnosis. Authors found a marked reduction in the risk of breast cancer in people with coeliac disease and the mechanism of this merits further attention as it may provide insight into the aetiology of this common malignancy.
ACCESSION #
13218835

 

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