Hepcidin: what every gastroenterologist should know
- Liver disease in transfusion dependent thalassaemia major. Li, C. K.; Chik, K. W.; Lam, C. W. K.; To, K. F.; Yu, S. C. H.; Lee, V.; Shing, M. M. K.; Cheung, A. Y. K.; Yuen, P. M. P. // Archives of Disease in Childhood;May2002, Vol. 86 Issue 5, p344
Aims: To study the prevalence and severity of liver diseases of transfusion dependent thalassaemia major patients, and correlate the histological and biochemical changes of iron overload in liver with the peripheral blood markers. Method: Liver biopsy was performed to assess the histological...
- Iron sucrose. // Reactions Weekly;4/28/2012, Issue 1399, p19
The article describes the case of a 65-year-old man who developed hypophosphataemic osteomalacia while being treated with iron sucrose.
- iron overload. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1233
A definition of the term "iron overload," which refers to organ failure due to too much accumulation of iron in the body, is presented.
- iron deficiency and exercise. // IDEA Fitness Journal;Oct2006, Vol. 3 Issue 9, p115
The article offers information on the importance of the mineral iron for athletes and for individuals who regularly exercise. Iron affects physical performance since it has a role in oxygen transport in the human body. Physically active people, especially athletes are more prone to iron losses...
- iron:. Huber, Jeffrey T.; Gillaspy, Mary L. // Encyclopedic Dictionary of AIDS-Related Terminology;2000, p124
A definition of the term "iron" is presented. It refers to a metallic element found in certain minerals, nearly all soils, and mineral waters. It is an essential component of hemoglobin, cytochrome, and other components of respiratory enzyme systems. The element transports oxygen to tissues and...
- haem. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p354
An encyclopedia entry for "haem" is presented. It refers to an iron-bearing pigment that integrates with globin in order to form hemoglobin, which is red blood cells' main component. Transportation of of the haem from the lungs to the tissues involves binding with oxygen.
- Mild iron overload in patients carrying the HFE S65C gene mutation: a retrospective study in patients with suspected iron overload and healthy controls. Holmstróm, P.; Marmur, J.; Eggertsen, G.; Gåfvels, M.; Stål, P. // Gut;Nov2002, Vol. 51 Issue 5, p723
Background and aims: The role of the HFE S65C mutation in the development of hepatic iron overload is unknown. The aim of the present study was: (A) to determine the HFE S65C frequency in a Northern European population; and (B) to evaluate whether the presence of the HFE S65C mutation would...
- Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). Peyssonnaux1,2, Carole; Zinkernagel, Annelies S.; Schuepbach, Reto A.; Rankin, Erinn; Vaulont, Sophie; Haase, Volker H.; Nizet, Victor; Johnson, Randall S. // Journal of Clinical Investigation;Jul2007, Vol. 117 Issue 7, p1926
Iron is essential for many biological processes, including oxygen delivery, and its supply is tightly regulated. Hepcidin, a small peptide synthesized in the liver, is a key regulator of iron absorption and homeostasis in mammals. Hepcidin production is increased by iron overload and decreased...
- The Role of Iron Metabolism in Lung Inflammation and Injury. Jonghan Kim; Wessling-Resnick, Marianne // Journal of Allergy & Therapy;Special2012, Vol. 3 Issue S, Special section p1
Iron is required for many vital functions including oxygen transport and energy metabolism. Protective mechanisms maintain optimal iron concentration involving dynamic regulation of the transporters and iron storage proteins. In addition to these systemic regulatory mechanisms, the unique lung...