Probiotics in inflammatory bowel disease: is it all gut flora modulation?

Ghosh, S.; van Heel, D.; Playford, R. J.
May 2004
Gut;May2004, Vol. 53 Issue 5, p620
Academic Journal
There is considerable public, media and scientific interest in "natural" products, including probiotics, in modulating intestinal inflammation and health. Intestinal microflora are intimately involved in the generation of immunocompetent cells and tuning the balance between T helper 1 immunity during the development of the gut associated immune system. It is now generally accepted that the intestinal bacterial flora contributes significantly to the pathogenesis of inflammatory bowel disease (IBD) along with mucosal immune dysregulation and genetic susceptibility.


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