Long term sequelae of bronchopulmonary dysplasia (chronic lung disease of infancy)

Eber, E.; Zach, M. S.
April 2001
Thorax;Apr2001, Vol. 56 Issue 4, p317
Academic Journal
journal article
Bronchopulmonary dysplasia (BPD) is the most common form of chronic lung disease in infancy. The clinical, radiological, and pathological features of BPD were first described a little more than three decades ago. The disease was then seen in large preterm infants with severe respiratory distress syndrome who had been treated with high inspired oxygen concentrations and prolonged mechanical ventilation with high positive airway pressures resulting in inflammation, fibrosis, and smooth muscle hypertrophy in the airways. Despite advances in the prevention and management of respiratory distress syndrome, neonatal chronic lung disease is still one of the major complications in mechanically ventilated premature infants.


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