Suh, Kathryn N.; Kain, Kevin C.; Keystone, Jay S.
May 2004
CMAJ: Canadian Medical Association Journal;5/25/2004, Vol. 170 Issue 11, p1693
Academic Journal
Malaria is a parasitic infection of global importance. Although rela-tively uncommon in developed countries, where the disease occurs mainly in travellers who have returned from endemic regions, it re-mains one of the most prevalent infections of humans worldwide. In endemic regions, malaria is a significant cause of morbidity and mortality and creates enormous social and economic burdens. Cur-rent efforts to control malaria focus on reducing attributable mor-bidity and mortality. Targeted chemoprophylaxis and use of insecti-cide- treated bed nets have been successful in some endemic areas. For travellers to malaria-endemic regions, personal protective mea-sures and appropriate chemoprophylaxis can significantly reduce the risk of infection. Prompt evaluation of the febrile traveller, a high degree of suspicion of malaria, rapid and accurate diagnosis, and appropriate antimalarial therapy are essential in order to opti-mize clinical outcomes of infected patients. Additional approaches to malaria control, including genetic manipulation of mosquitoes and malaria vaccines, are areas of ongoing research.


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