Quality of life assessment in gastro-oesophageal reflux disease
- Stress-related changes in oesophageal permeability: filling the gaps of GORD? Söderholm, Johan D. // Gut;Sep2007, Vol. 56 Issue 9, p1177
Albeit remaining a controversial issue, it has become increasingly recognised that psychological stress has a major impact on gut mucosal function and affects the course of gastrointestinal disorders. Research during the last decade has shown that stress causes barrier dysfunction of the...
- Review: Sparse evidence supports lifestyle modifications for reducing symptoms of gastroesophageal reflux disease. // ACP Journal Club;Sep/Oct2006, Vol. 145 Issue 2, p44
The article focuses on a study, which examines lifestyle modifications for reducing symptoms of gastroesophageal reflux disease (GERD). A standard scoring system with 5 levels of evidence was used to assess the quality of studies. Lower esophageal sphincter pressure and heartburn symptoms are...
- Patient-Derived Health State Utilities for Gastroesophageal Reflux Disease. Gerson, Lauren B.; Ullah, Nighat; Hastie, Trevor; Triadafilopoulos, George; Goldstein, Mary // American Journal of Gastroenterology;Mar2005, Vol. 100 Issue 3, p524
BACKGROUND AND AIMS: Gastroesophageal reflux disease is a chronic disease that adversely affects health-related quality of life. The purpose of this study was to derive health state utilities for patients with chronic heartburn symptoms.METHODS: We used a custom-designed computer program in...
- THE ORACLE (OESOPHAGEAL REFLUX AND CHANGE IN LIFESTYLE EVALUATION) STUDY. Sivaji, G.; Corbett, S.; Podbur, S.; Welfare, M.; Gray, J. C.; Thomas, R. K. // Gut;Apr2004 Supplement 3, Vol. 53, pA57
Gastro-oesophageal reflux disease (GORD) has significant impact on health and quality of life. An ideal treatment for GORD should improve reflux symptoms and the health related quality of life. Several studies exploring the causal factors of GORD have yielded conflicting reports. The rise of the...
- Health-related quality of life improves with treatment-related GERD symptom resolution after adjusting for baseline severity. Revicki, Dennis A.; Zodet, Marc W.; Joshua-Gotlib, Sandra; Levine, Douglas; Crawley, Joseph A. // Health & Quality of Life Outcomes;2003, Vol. 1, p73
Severity and frequency of gastroesophageal reflux disease (GERD) related symptoms are associated with impaired health-related quality of life (HRQL). This study evaluated the association between baseline heartburn severity and endpoint HRQL of patients treated for heartburn and the relationship...
- GERD BEYOND THE ESOPHAGUS. Magill-Lewis, Jillene // Drug Topics;4/15/2002, Vol. 146 Issue 8, p62
Provides information on the gastroesophageal reflux disease. Symptoms; Developments in drugs for treatment of the disease; Role of pharmacists in the treatment of the disease.
- hard to swallow. Drury, Kathryn // Vegetarian Times;Apr2001, Issue 284, p68
Focuses on gastroesophageal reflux disease (GERD), a condition characterized by frequent occurrence of heartburn. Pathophysiology; Causes; Foods that can help relieve the pain; Role of stress in increasing risks for GERD.
- Reducing stress won't quench those fiery heartburn pains. Letsche, Amber Lee // Fort Worth Business Press;6/22/2001, Vol. 14 Issue 8, p18
Corrects misconceptions that stress causes heartburn. Heartburn as a symptom of gastroesophageal reflux disease (GERD); Causes of GERD; Ways in which stress can aggravate heartburn.
- Omeprazole Versus High-Dose Ranitidine in Mild Gastroesophageal Reflux Disease: Short- and Long-Term Treatment. Fesien, Henk P. M.; Schenk, Ed; Gie Tan; Snel, Pleun; Nelis, Frits // American Journal of Gastroenterology;Apr1999, Vol. 94 Issue 4, p931
OBJECTIVE: Patients with reflux esophagitis suffer from a chronic condition that may cause considerable discomfort because of recurrent symptoms and diminished quality of life. This study was designed to evaluate acute and long-term treatment comparing standard doses of omeprazole and high-dose...