Opening the Door for Stem Cell Progress
Tags: STEM cells -- Research; RESEARCH -- Law & legislation; NEURAL stem cells -- Transplantation; CELL transplantation
Related Articles
- Brain Tumor Tropism of Transplanted Human Neural Stem Cells Is Induced by Vascular Endothelial Growth Factor. Schmidt, Nils Ole; Przylecki, Wojciech; Yang, Wendy; Ziu, Mateo; Yang Teng; Seung U. Kim; Black, Peter Mcl.; Aboody, Karen S.; Carroll, Rona S. // Neoplasia;Jun2005, Vol. 7 Issue 6, p623
The transplantation of neural stem cells (NSCs) offers a new potential therapeutic approach as a cell-based delivery system for gene therapy in brain tumors. This is based on the unique capacity of NSCs to migrate throughout the brain and to target invading tumor cells. However, the signals...
- Reconstructing neural circuits using transplanted neural stem cells in the injured spinal cord. Tamir Ben-Hur // Journal of Clinical Investigation;Sep2010, Vol. 120 Issue 9, p3096
Traumatic spinal cord injury is one of the most common causes of disability in young adults. Restoring independent ambulation in such patients is considered one of the biggest challenges in regenerative medicine because repair of spinal cord injury involves the complex processes of axonal...
- A rat model for studying neural stem cell transplantation. Xue-mei ZHOU; Jing-bo SUN; Hui-ping YUAN; Dong-lai WU; Xin-rong ZHOU; Da-wei SUN; Hong-yi LI; Zheng-bo SHAO; Zhi-ren ZHANG // Acta Pharmacologica Sinica;Nov2009, Vol. 30 Issue 11, p1496
AbstractAim:The goal of this project was to develop a rat model for neural stem cell (NSC) transplantation studies in which NSCs were modified with brain-derived neurotrophic factor (BDNF) genes that may permit extensive and reliable analysis of the transplants.Methods:NSCs were cultured and...
- Neural Stem Cells as Biological Minipumps: A Faster Route to Cell Therapy for the CNS? Chen, Isaac; Bakshi, Asha; Royo, Nicolas C.; Magge, Suresh N.; Watson, Deborah J. // Current Stem Cell Research & Therapy;Jan2007, Vol. 2 Issue 1, p13
One strategy for the use of neural stem cells (NSCs) in treating neurological disorders is as transplantable "biological minipumps", in which genetically engineered neural stem cells serve as sources of secreted therapeutic (neuroprotective or tumoricidal) agents. Neural stem cells are highly...
- Intravenous Implanted Neural Stem Cells Migrate to Injury Site, Reduce Infarct Volume, and Improve Behavior after Cerebral Ischemia. Chiung-Chyi Shen; Chen-Huan Lin; Yi-Chin Yang; Ming-Tsang Chiao; Wen-Yu Cheng; Jiunn-Liang Ko // Current Neurovascular Research;Aug2010, Vol. 7 Issue 3, p167
No abstract available.
- Neuroprotection: The Emerging Concept of Restorative Neural Stem Cell Biology for the Treatment of Neurodegenerative Diseases. Carletti, Barbara; Piemonte, Fiorella; Rossi, Ferdinando // Current Neuropharmacology;Jun2011, Vol. 9 Issue 2, p313
No abstract available.
- Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the mongolian gerbil. // Molecular Brain;2011, Vol. 4 Issue 1, p35
The article presents a study focusing on how transplantation of human neural stem or progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the mongolian gerbil. The findings of the study suggest the use of hGal1 in combination with transplantation...
- Direct Generation of Neurosphere-Like Cells from Human Dermal Fibroblasts. Soon-Tae Lee; Kon Chu; Keun-Hwa Jung; Young-Mi Song; Daejong Jeon; Seung U. Kim; Manho Kim; Sang Kun Lee; Jae-Kyu Roh // PLoS ONE;2011, Vol. 6 Issue 7, p1
Neural stem cell (NSC) transplantation replaces damaged brain cells and provides disease-modifying effects in many neurological disorders. However, there has been no efficient way to obtain autologous NSCs in patients. Given that ectopic factors can reprogram somatic cells to be pluripotent, we...
- Parkinson's Patient Treated with Own Neural Stem Cells. TOWNSEND, LIZ // National Right to Life News;Mar2009, Vol. 36 Issue 3, p6
The article discusses research being done on a successful treatment of Parkinson's disease with the patient's own neural stem cells. It references a study by Michel F. Levesque and his colleagues, published in the "Bentham Open Stem Cell Journal." The research demonstrated how the researchers...
