Impact of Age on the Outcome of Liver Resections

Aldrighetti, Luca; Arru, Marcella; Calori, Giliola; Caterini, Roberto; Comotti, Laura; Torri, Giorgio; Ferla, Gianfranco
May 2004
American Surgeon;May2004, Vol. 70 Issue 5, p453
Academic Journal
The purpose of this study was to evaluate the influence of age on the outcome of liver resections. One hundred five consecutive hepatic resections were divided into two groups: ≥65 years old [old group (O-group)) and <65 years old [young group (Y-group)]. The two groups were first compared to evaluate the distribution of the variables potentially affecting the postoperative course, including primary diagnosis, concomitant diseases, previous upper abdominal surgery, type of operation (major or minor resection), associated procedures, presence and length of portal clamping, intraoperative blood losses and transfusions, and length of operation. The outcome of hepatic resections in the two groups was comparatively evaluated in terms of postoperative mortality, morbidity, transfusions, and length of postoperative hospitalization. The Y-group included 61 resections in 60 patients, mean age 52 ± 10 years (mean ± SD ), range 23-64 years, whereas the O-group included 44 resections in 43 patients, mean age 71 ± 4 years (mean ± SD ), range 65-82 years. The O-group included more hepatocellular carcinomas (45.4% vs 18.0%, P = 0.002) and chronic liver diseases (40.9% vs 18.7%, P = 0.017); the median length of operation was slightly higher in the Y-group (300 minutes vs 270 minutes, P = 0.003). Both O-group and Y-group were comparable (P = n.s.) when evaluated for all other listed variables. As far as concerns the outcome of hepatic resections in the two groups, the length of postoperative hospitalization was identical (median 9 days, 5-60 days), whereas transfusions of packed red cells (O-group vs Y-group: 25.0% vs 16.3%, P = 0.30) or fresh frozen plasma (O-group vs Y-group: 13.6% vs 6.5%, P = 0.053) were not statistically different. Postoperative mortality included one case among young patients whereas no deaths were recorded among elderly patients. Postoperative morbidity was higher in Y-group than in...


Related Articles

  • Enhanced Recovery Pathway for Urgent Colectomy. Roulin, Didier; Blanc, Catherine; Muradbegovic, Mirza; Hahnloser, Dieter; Demartines, Nicolas; Hübner, Martin // World Journal of Surgery;Aug2014, Vol. 38 Issue 8, p2153 

    Background: Enhanced recovery protocols have been proven to decrease complications and hospital stay following elective colorectal surgery. However, these principles have not yet been reported for urgent surgery procedures. We aimed to assess our initial experience with urgent colectomies...

  • Perioperative risk assessment for hepatocellular carcinoma by using the MELD score. Delis, Spiros G.; Bakoyiannis, Andreas; Dervenis, Christos; Tassopoulos, Nikos // Journal of Gastrointestinal Surgery;Dec2009, Vol. 13 Issue 12, p2268 

    Background/aims: The aim of this study was to evaluate the ability of Model for End-Stage Liver Disease (MELD) in predicting post hepatectomy outcome for hepatocellular carcinoma (HCC).Methods: Between 2001 and 2005, 94 cirrhotic patients with HCC underwent hepatectomy...

  • BOWEL RESECTION. Shriner, Walter // American Journal of Gastroenterology;May1962, Vol. 37 Issue 5, p508 

    Discusses the important factors in the pre-operative and post-operative care of bowel resection surgery. Overview of the physiology of the colon; Inclusion of mechanical cleansing of the bowel with adequate sterilization in the preoperative procedures; Importance of analgesics in the...

  • Surgical Treatment and Complications of Treating Pancreatic Tumor. Mesic, Deso; Rifatbegovic, Zijah; Ljuca, Farid; Agic, Mirha; Mehmedagic, Indira; Sakic, Enver; Ahmetasevic, Emir; Sibincic, Sanja; Hotic, Nesad; Kovacevic, Maja; Jusufovic, Rasim; Rahmanovic, Emir // Medicinski Arhiv;2011, Vol. 65 Issue 5, p308 

    Pancreatic tumor is one with the worst prognosis of all cancers, and the tenth most frequent cancer in Europe, making the 3% of all cancers affecting both sexes. Most patients seek treatment when the disease is in its advanced stage and the level for possible resectability is low. Late...

  • Recurrent Myofibrosarcoma of the Sinonasal Tract Treated with Postoperative Radiation Therapy. Uslu, Gonca H.; Topkan, Erkan; Ersoz, Safak; Isik, A. Umit // International Journal of Hematology & Oncology / UHOD: Uluslarar;Jun2010, Vol. 20 Issue 2, p55 

    Myofibrosarcomas (MFSs) of the sinonasal tract are exceedingly rare tumors in adults. The principle treatment of MFS of the head and neck is surgical. However, aggressive surgery is not only debilitating, functionally and cosmetically, but tumor free margins are often difficult to obtain because...

  • The efficacy of spleen-preserving distal pancreatectomy with or without splenic vessel preservation: a meta-analysis. Yu Tang; Shanhong Tang; Sanyuan Hu // International Journal of Clinical & Experimental Medicine;2015, Vol. 8 Issue 10, p17128 

    Background: Spleen-preserving distal pancreatectomy can be performed with splenic vessel preservation (SPDP-SVP) or splenic vessel resection (SPDP-SVR). This meta-analysis aimed to evaluate the clinical outcomes of patients undergoing SPDP-SVP or SPDP-SVR. Method: A systematic literature search...

  • Impact of Advanced Age on the Outcome of Liver Resection World J. Surg. Vol. 27, No. 10, October 2003. Aldrighetti, Luca; Arru, Marcella; Caterini, Roberto; Finazzi, Renato; Comotti, Laura; Torri, Giorgio; Ferla, Gianfranco // World Journal of Surgery;Oct2003, Vol. 27 Issue 10, p1149 

    The aim of this retrospective study was to evaluate the influence of age on the outcome of liver resection. A total of 129 consecutive liver resections were divided into two groups: ≥ 70 years old [old group (O-group)] and < 70 years old [young group (Y-group)]. The two groups were first...

  • Intentionally curative treatment of locally recurrent rectal cancer: a systematic review. Tanis, Pieter J.; Doeksen, Annemiek; van Lanschot, J. Jan B. // Canadian Journal of Surgery;Apr2013, Vol. 56 Issue 2, p135 

    Background: There is a lack of outcome data beyond local recurrence rates after primary treatment in rectal cancer, despite more information being necessary for clinical decision-making. We sought to determine patient selection, therapeutic modalities and outcomes of locally recurrent rectal...

  • Comparison of P-POSSUM and O-POSSUM in predicting mortality after oesophagogastric resections. Nagabhushan, J. S.; Srinath, S.; Weir, F.; Angerson, W. J.; Sugden, B. A.; Morran, C. G. // Postgraduate Medical Journal;May2007, Vol. 83 Issue 979, p355 

    Background: P-POSSUM (Physiological and Operative Severity Score for the enumeration of Mortality and morbidity) predicts mortality and morbidity in general surgical patients providing an adjunct to surgical audit. 0-POSSUM was designed specifically to predict mortality and morbidity in patients...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics