TITLE

Pneumococcal Endocarditis in Children

AUTHOR(S)
Givner, Laurence B.; Mason Jr., Edward O.; Tan, Tina Q.; Barson, William J.; Schutze, Gordon E.; Wald, Ellen R.; Bradley, John S.; Hoffman, Jill; Yogev, Ram; Kaplan, Sheldon L.
PUB. DATE
May 2004
SOURCE
Clinical Infectious Diseases;5/1/2004, Vol. 38 Issue 9, p1273
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Endocarditis due to Streptococcus pneumoniae is unusual in children, accounting for 3%-7% of all cases of childhood endocarditis. The US Pediatric Multicenter Pneumococcal Surveillance Group has prospectively identified patients with invasive disease at 8 children's hospitals. During the period of 1 September 1993 through 28 February 2003, a total of 11 children with pneumococcal endocarditis were seen. Seven (64%) were 3-36 months old; 8 (73%) were boys. Ten (91%) had preexisting structural heart disease; 5 had undergone previous heart surgery. Concomitant sites of infection were noted in 6 patients (55%), including 3 patients with meningitis. One patient (9%) died during hospitalization, and 5 others (45%) experienced serious complications. Only 2 patients remained hospitalized for their entire course of parenteral antibiotic therapy. Eight of 10 pneumococcal isolates tested were vaccine or vaccine-related serotypes included in the currently licensed 7-valent conjugated pneumococcal vaccine. Pneumococcal endocarditis in children is unusual but often has serious complications.
ACCESSION #
13058699

 

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