Easing the Burden: Characterizing the Disease Burden of Neonatal Group B Streptococcal Disease to Motivate Prevention

Schrag, Stephanie J.; Schuchat, Anne
May 2004
Clinical Infectious Diseases;5/1/2004, Vol. 38 Issue 9, p1209
Academic Journal
This article focuses on the incidence and characteristics of invasive disease due to group B streptococci (GBS) among neonatal in Great Britain and Wales. Development and licensure of an adolescent or maternal GBS vaccine is likely the most effective and sustainable longterm prevention strategy for a wide range of hospital settings and countries. If immunity does not wane rapidly, a single vaccine series may be sufficient to protect women throughout their childbearing years. Although adolescent vaccination strategies would alleviate concerns about vaccination during pregnancy and might prevent adverse outcomes during early pregnancy.


Related Articles

  • Vaccination and pregnancy.  // Pulse;11/26/2008, Vol. 68 Issue 41, p47 

    The article focuses on the theoretical consideration and data from the inadvertent application of vaccines and drugs in pregnancy which tends to drive recommendations. According to the article, one of the concerns is the potential adverse effect of febrile reactions to vaccines. It is stated...

  • Pneumococcal Immunization: From Policy to Practice. Schwartz, Benjamin; Breiman, Robert F. // JAMA: Journal of the American Medical Association;9/5/90, Vol. 264 Issue 9, p1154 

    Editorial. Deals with the low utilization of pneumococcal vaccines targeted for adults in the U.S. Factors behind the lack of use of pneumococcal vaccines; Strategies that can be adopted to increase utilization of pneumococcal vaccines; Cost benefits of immunization.

  • General considerations.  // WHO Technical Report Series;2004, Issue 927, p66 

    The article focuses on polysaccharide vaccines for infections caused by Streptococcus pneumoniae, which are responsible for substantial morbidity and mortality, commonly on children and the elderly. Pneumociccus are classified based on chemical and serological distinct capsular polysaccharides....

  • New children's vaccines, new direction. Kassianos, George // GP: General Practitioner;1/12/2007, p30 

    The article focuses on issues related to the introduction of routine immunization of infants against pneumococcal disease in Great Britain. The new immunization schedule was announced on June 12, 2006. One of the problems of introducing a new vaccine is how to fit another vaccine into the...

  • Prevenar joins schedule in June. Reid, Stewart // New Zealand Doctor;5/7/2008, p17 

    The article focuses on the use of Prevenar as vaccine. According to the author, starting June 1, 2008 heptavalent conjugate pneumococcal vaccine Prevenar will be part of the New Zealand routine immunization schedule. The immunization will have a four-dose schedule with doses at six weeks, three,...

  • Indirect Effect of Conjugate Vaccine on Adult Carriage of Streptococcus pneumoniae: An Explanation of Trends in Invasive Pneumococcal Disease. Hammitt, Laura L.; Bruden, Dana L.; Butler, Jay C.; Baggett, Henry C.; Hurlburt, Debby A.; Reasonover, Alisa; Hennessy, Thomas W. // Journal of Infectious Diseases;6/1/2006, Vol. 193 Issue 11, p1487 

    Background. Use of heptavalent protein-polysaccharide pneumococcal conjugate vaccine (PCV7) has been associated with decreases in PCV7-type invasive pneumococcal disease and nasopharyngeal (NP) carriage in children. Vaccine use has also indirectly decreased the rate of invasive disease in...

  • Differential Effects of Pneumococcal Vaccines against Serotypes 6A and 6C. Park, In H.; Moore, Matthew R.; Treanor, John J.; Pelton, Stephen I.; Pilishvili, Tamara; Beall, Bernard; Shelly, Mark A.; Mahon, Barbara E.; Nahm, Moon H. // Journal of Infectious Diseases;12/15/2008, Vol. 198 Issue 12, p1818 

    Background. Because classic pneumococcal serotyping methods cannot distinguish between serotypes 6A and 6C, the effects of pneumococcal vaccines against serotype 6C are unknown. Pneumococcal vaccines contain serotype 6B but not serotypes 6A and 6C. Methods. We used a phagocytic killing assay to...

  • In the mood for wiping out vaccine-preventable diseases. Fleck, Fiona // Bulletin of the World Health Organization;Apr2014, Vol. 92 Issue 4, p236 

    An interview with executive vice president of the Sabin Vaccine Institute, Ciro de Quadros, is presented. He discusses how he became interested in immunization while involved with a smallpox programme in Brazil in 1969, what disease surveillance and containment is and how he helped to develop...

  • Transmission of Streptococcus pneumoniaein Rural Gambian Villages: A Longitudinal Study. Hill, Philip C.; Townend, John; Antonio, Martin; Akisanya, Biodun; Ebruke, Chinelo; Lahai, George; Greenwood, Brian M.; Adegbola, Richard A. // Clinical Infectious Diseases;6/1/2010, Vol. 50 Issue 11, p1468 

    Background. To prepare for national introduction of a pneumococcal vaccine of restricted valency, we studied the pattern of nasopharyngeal carriage of Streptococcus pneumoniae and its transmission in Gambian villages over time. Methods. We collected nasopharyngeal swab specimens every 2 weeks...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics