TITLE

DNA, PNA, and Their Derivatives for Precise Genotyping of SNPs

AUTHOR(S)
Kuzuya, A.; Zhou, J.-M.; Komiyama, M.
PUB. DATE
January 2004
SOURCE
Mini-Reviews in Organic Chemistry;Jan2004, Vol. 1 Issue 1, p125
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Two new approaches for SNP genotyping are described. The one is based on tandem site-selective RNA scission and the genotype is determined by MALDI-TOF/MS analyses of clipped short RNA. The other is visual SNP genotyping with combinations of peptide nucleic acid (PNA) and single-stranded DNA specific nucleases.
ACCESSION #
13030066

Tags: GENETIC polymorphisms;  DNA;  NUCLEIC acids;  RNA;  GENETICS;  BIOMOLECULES

 

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