DNA, PNA, and Their Derivatives for Precise Genotyping of SNPs

Kuzuya, A.; Zhou, J.-M.; Komiyama, M.
January 2004
Mini-Reviews in Organic Chemistry;Jan2004, Vol. 1 Issue 1, p125
Academic Journal
Two new approaches for SNP genotyping are described. The one is based on tandem site-selective RNA scission and the genotype is determined by MALDI-TOF/MS analyses of clipped short RNA. The other is visual SNP genotyping with combinations of peptide nucleic acid (PNA) and single-stranded DNA specific nucleases.


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