Endothelin and vascular function in liver disease

Moore, K.
February 2004
Gut;Feb2004, Vol. 53 Issue 2, p159
Academic Journal
The endothelins are a group of three related peptides with two receptor subtypes, ETA and ETB. Following the discovery of endothelin 1 as a potent vasoconstrictor, there has been intense interest in the role of endothelin on vascular function in liver disease. Speculation on the role of endothelin in the pathogenesis of acute renal failure, including hepatorenal syndrome, has also been speculated.


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