TITLE

Summary

AUTHOR(S)
Costa, M.; Glise, H.; Graffner, H.
PUB. DATE
March 2004
SOURCE
Gut;Mar2004 Supplement 2, Vol. 53, pii22
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Neural information from the viscera to the central nervous system (CNS) plays a very important role in health and disease. Afferent neural activity from the gastrointestinal tract signals the CNS but the nature of the stimuli required to activate the visceral afferent neurones is still not well defined. Greater comprehension of the anatomy of visceral afferents and of the underlying mechanisms relating to visceral mechano- and chemoreception is required in order to identity rational therapeutic targets for the treatment of functional gastrointestinal diseases.
ACCESSION #
12998629

 

Related Articles

  • What activates visceral afferents? Gruncly, D. // Gut;Mar2004 Supplement 2, Vol. 53, pii5 

    Vagal and spinal afferents represent the information superhighways that convey sensory information from the gut to the central nervous system. These afferents are sensitive to both mechanical and chemical stimuli. Vagal afferents terminate in the muscle layers and in the mucosa. Muscle afferents...

  • Appendix.  // Applied Clinical Trials;Jun2011, Vol. 20 Issue 6, p60 

    An appendix is presented on the examination of the central nervous system (CNS) pathways involved in pain, perception, and modulation.

  • Sensitisation of gastrointestinal tract afferents. McMahon, S. B. // Gut;Mar2004 Supplement 2, Vol. 53, pii13 

    Sensory innervation of the viscera serves a number of important functions, including regulation of visceral motility and secretory activity, and transmission of visceral sensations, including pain. There are many ways in which the sensitivity of visceral sensory neurones might be modulated, and...

  • RectalHyposensitivity: A Disorder of the Rectal Wall or the Afferent Pathway? An Assessment Using the Barostat. Gladman, Marc A.; Dvorkin, Lee S.; Lunniss, Peter J.; Williams, Norman S.; Scott, S. Mark // American Journal of Gastroenterology;Jan2005, Vol. 100 Issue 1, p106 

    OBJECTIVES: Rectalhyposensitivity (RH) relates to a diminished perception of rectal distension. Diagnosis on the basis of abnormal threshold volumes on balloon distension alone may be inaccurate due to the influence of differing rectal wall properties. The aim of this study was to investigate...

  • Visceral perception: sensory transduction in visceral afferents and nutrients. Raybould, H.E. // Gut;Jul2002 Supplement 1, Vol. 51, pI11 

    The possible mechanisms that may be involved in nutrient detection in the wall of the gastrointestinal tract are reviewed. There is strong functional and electrophysiological evidence that both intrinsic and extrinsic primary afferent neurones mediate mechanoand chemosensitive responses in the...

  • A Robust Co-Localisation Measurement Utilising Z-Stack Image Intensity Similarities for Biological Studies. Yinhai Wang; Ledgerwood, Craig; Grills, Claire; Fitzgerald, Denise C.; Hamilton, Peter W. // PLoS ONE;Feb2012, Vol. 7 Issue 2, p1 

    Background: Co-localisation is a widely used measurement in immunohistochemical analysis to determine if fluorescently labelled biological entities, such as cells, proteins or molecules share a same location. However the measurement of colocalisation is challenging due to the complex nature of...

  • Electro-acupuncture Reduces Neuronal Apoptosis Linked to Bax and Bcl-2 Expression in the Spinal Cords of Cats Subjected to Partial Dorsal Root Ganglionectomy. Qi Zhao; Jia Liu; Xin-Yun Xu; Wei-Wei Sun; Xue Zhou // Neurochemical Research;Nov2008, Vol. 33 Issue 11, p2214 

    Abstract  While electro-acupuncture (EA) has been well known to contribute towards neuroplasticity occurring in both the central and the peripheral nervous system after injury, the underlying mechanism remains largely unknown. This study evaluated the effects and the possible mechanism of...

  • Effects of Electro-acupuncture on PDGF Expression in Spared Dorsal Root Ganglion and Associated Dorsal Horn Subjected to Partial Dorsal Root Ganglionectomy in Cats. Wei-Wei Sun; Wei Zhao // Neurochemical Research;Mar2008, Vol. 33 Issue 3, p437 

    Abstract  The effects of electro-acupuncture (EA) on the expression of platelet derived growth factor (PDGF) in spared dorsal root ganglion (DRG) and associated dorsal horns were evaluated in cats subjected to bilateral removal of L1–L5 and L7–S2 DRG,...

  • afferent nerve.  // Hutchinson Dictionary of Scientific Biography;2005, p1 

    Nerve that carries impulses toward the central nervous system (that is, the spinal cord or brain).

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics