TITLE

Highly positive intraoperative fluid balance during cardiac surgery is associated with adverse outcome

AUTHOR(S)
Toraman, Fevzi; Evrenkaya, Serdar; Yuce, Murat; Turek, Onur; Aksoy, Nazan; Karabulut, Hasan; Demirhisar, Onder; Alhan, Cem
PUB. DATE
March 2004
SOURCE
Perfusion;Mar2004, Vol. 19 Issue 2, p85
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Hemodilution and increase in capillary permeability occurring with cardiopulmonary bypass (CPB) impose a risk for tissue edema and blood transfusion that may result in an increased complication rate after coronary artery bypass grafting (CABG). Of the 1280 consecutive patients undergoing isolated on-pump CABG, total fluid balance at the end of the operation was less than or equal to 500 mL in 1155 (Group 1) and more than 500 mL in 125 (Group 2). During CPB, blood was added to the reservoir only when the hematocrit fell to 17% or less and crystalloid solution only when the pump flow index fell below 2.0 L/min/m2. Anesthetic, surgical, and postoperative management and diagnoses were the same in all patients, and a single surgical and anesthesia team performed all operations. No patient was excluded from the study. This study suggests that intraoperative volume overload increases blood transfusion and length of hospital stay in patients undergoing CABG.
ACCESSION #
12972931

 

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