COPD: imaging and clinical aspects

December 2003
Thorax;Dec2003 Supplement 3, Vol. 58, piii72
Academic Journal
The natural history of chronic obstructive pulmonary disease (COPD) is characterized by a progressive decline in ventilatory function and has been studied extensively using the FEY1. However, COPD is heterogeneous with variable contribution from emphysema or intrinsic airway disease, which is not differentiated by this test alone. Nuclear scintigraphy techniques have been used previously for the detection of air trapping, however these are limited in sensitivity, spatial resolution and by their use of ionising radiation. This study aims to investigate the pattern of lung ventilation seen in dynamic MR imaging particularly with a view to detecting air trapping in COPD patients.


Related Articles

  • Automated lobar quantification of emphysema in patients with severe COPD. Revel, Marie-Pierre; Faivre, Jean-Baptiste; Remy-Jardin, Martine; Deken, Valérie; Duhamel, Alain; Marquette, Charles-Hugo; Tacelli, Nunzia; Bakai, Anne-Marie; Remy, Jacques // European Radiology;Dec2008, Vol. 18 Issue 12, p2723 

    Automated lobar quantification of emphysema has not yet been evaluated. Unenhanced 64-slice MDCT was performed in 47 patients evaluated before bronchoscopic lung-volume reduction. CT images reconstructed with a standard (B20) and high-frequency (B50) kernel were analyzed using a dedicated...

  • Chronic obstructive pulmonary disease · 2: Pathology and biochemistry of emphysema. Hogg, J.C.; Senior, R.M. // Thorax;Sep2002, Vol. 57 Issue 9, p830 

    Part 2. Examines the pathology and biochemistry of emphysema. Cells responsible for the degradation of extracellular matrix in emphysema; Proteinase-antiproteinase hypothesis; Proteinases involved in alveolar septal destruction.

  • Influence of lung volume reduction surgery (LVRS) on health related quality of life in patients with chronic obstructive pulmonary disease. Goldstein, R.S.; Todd, T.R.J.; Guyatt, G.; Keshavjee, S.; Dolmage, T.E.; van Rooy, S.; Krip, B.; Maltais, F.; LeBlanc, P.; Pakhale, S.; Waddell, T.K. // Thorax;May2003, Vol. 58 Issue 5, p405 

    Background: The clinical value of LVRS has been questioned in the absence of trials comparing it with pulmonary rehabilitation, the prevailing standard of care in COPD. Patients with heterogeneous emphysema are more likely to benefit from volume reduction than those with homogeneous disease....

  • Chronic Obstructive Pulmonary Disease. Torpy, Janet M. // JAMA: Journal of the American Medical Association;11/26/2008, Vol. 300 Issue 20, p2448 

    The article provides patient information about chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema. Signs and symptoms of the disease along with diagnoses and tests are provided. Spirometry, arterial blood gas sampling, and pulse oximetry are discussed....

  • Whole-lung densitometry versus visual assessment of emphysema. Cavigli, Edoardo; Camiciottoli, Gianna; Diciotti, Stefano; Orlandi, Ilaria; Spinelli, Cheti; Meoni, Eleonora; Grassi, Luca; Farfalla, Carmela; Pistolesi, Massimo; Falaschi, Fabio; Mascalchi, Mario // European Radiology;Jul2009, Vol. 19 Issue 7, p1686 

    We compared whole-lung densitometry with visual evaluation of pulmonary emphysema. Thirty patients with chronic obstructive pulmonary disease underwent multi-detector CT (150 mAs and 0.75 collimation) with double reconstruction: thick (5-mm) slices with smooth filter for whole-lung densitometry...

  • TESRA Study Results.  // MD Conference Express;Aug2011, p10 

    The article reports on the results of the Treatment of Emphysema with a Selective Retinoid Agonist (TESRA) research study, which was a Phase 2, double-blind, randomized, placebo controlled, multicenter trial that involved investigators at 69 centers in 12 countries and which evaluated the...

  • Pulmonx Gains Regulatory Approval for Expanded Labeling for Emphysema Treatment.  // Biomedical Market Newsletter;1/14/2012, Vol. 21, p1 

    The article presents information on the acquisition of regulatory approval for expanded labeling of Zephyr endobronchial valve (EBV) therapy for emphysema treatment by Pulmonx. It discusses the use of Zephyr EBV treatment as a safe and efficacious approach for managing the crippling...

  • Long-term results of lung volume reduction surgery. Fujimoto, T.; Teschler, H.; Hillejan, L.; Zaboura, G.; Stamatis, G. // European Journal of Cardio-Thoracic Surgery;Mar2002, Vol. 21 Issue 3, p483 

    Objective: Lung volume reduction surgery (LVRS) is effective in the short and intermediate term for the improvement of pulmonary function and subjective symptoms in selected patients with advanced emphysema. The purpose of this study was to examine the long-term functional results of LVRS and to...

  • Killer Emphysema. Roberson, Delores // Saturday Evening Post;Dec84, Vol. 256 Issue 9, p4 

    Presents two readers' reactions to an article on pulmonary emphysema published in the September 1984 issue of "The Saturday Evening Post" periodical.


Read the Article


Sign out of this library

Other Topics