TITLE

Asthma biology

PUB. DATE
December 2003
SOURCE
Thorax;Dec2003 Supplement 3, Vol. 58, piii60
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Fixed airflow obstruction occurs in a minority of patients with asthma and is associated with increased morbidity and mortality. To identify potential risk factors for the development of fixed airflow obstruction, researchers have investigated the association between post bronchodilator FEV and smoking, atopy, duration of symptoms, use of inhaled corticosteroids and induced sputum eosinophil and neutrophil counts. A minority of patients with asthma have refractory disease with poorly controlled symptoms, recurrent exacerbations and/or persistent airflow obstruction despite high dose inhaled or oral corticosteroids and additional bronchodilator therapy.
ACCESSION #
12965199

 

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