December 2001
Thorax;Dec2001 Supp, Vol. 56, piii50
Academic Journal
This article presents various studies related to genetic aspects of respiratory disease. Inspiratory muscle training using the TIRETM system has been demonstrated to induce low frequency fatigue, an indicator of muscle overload, in the diaphragm. CFA is characterised by various degrees of pulmonary interstitial and alveolar inflammation accompanied by fibrosis. The activated inflammatory cells produce cytokines, reactive oxygen species and other mediators of inflammation. Oxygen-derived free radicals are also released by phagocytic cells such as neutrophils and macrophages or are inhaled directly from the environment.


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