December 2001
Thorax;Dec2001 Supp, Vol. 56, piii37
Academic Journal
This article presents various studies related to cross infection and cystic fibrosis. Cystic fibrosis patients becoming infected with Burkholderia cepacia have a variable clinical course, ranging from asymptomatic detection, to a severe and potentially fatal pneumonia with gram negative shock and multi-organ failure, commonly referred to as "Cepacia syndrome." The determinants of clinical course are uncertain, and probably relate both to bacterial and host factors. It has been shown that patients with CF can become colonised by the same transmissible Pseudomonas aeruginosa strain and because such strains are frequently multiresistant, increased morbidity may result.


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