Aetiology and epidemiology

May 2002
Thorax;May2002 Supplement 1, Vol. 57, pi6
Academic Journal
The article discusses about the aetiology and epidemiology of community acquired pneumonia (CAP). studies of the aetiology of CAP are complicated by the low yield of blood culture,the difficulty in obtaining adequate sputum specimens,and the reluctance to perform lung aspiration and bronchoaveolar lavage in children. Studies of specific pathogens are summarised in the article. All of these were prospective studies in which pneumonia was community acquired and where the case definition includes clinical findings compatible with pneumonia together with radiological changes. It was revealed that, Streptococcus pneumoniae was the most common cause of pneumonia in childhood. Age was considered to be the good predictor of the likely pathogens.


Related Articles

  • Acute Otitis Media Caused by Moraxella catarrhalis: Epidemiologic and Clinical Characteristics. Broides, Arnon; Dagan, Ron; Greenberg, David; Givon-Lavi, Noga; Leibovitz, Eugene // Clinical Infectious Diseases;12/1/2009, Vol. 49 Issue 11, p1641 

    Background. This study describes the epidemiologic, microbiologic, and otologic features and selected signs and symptoms of acute otitis media (AOM) caused by Moraxella catarrhalis and compares them with AOM caused by other bacterial pathogens. Methods. Patients aged !5 years with...

  • Clinical and economic burden of community-acquired pneumonia among adults in Europe. Welte, T.; Torres, A.; Nathwani, D. // Thorax;Jan2012, Vol. 67 Issue 1, p71 

    It is difficult to determine the impact of community-acquired pneumonia (CAP) in Europe, because precise data are scarce. Mortality attributable to CAP varies widely between European countries and with the site of patient management. This review analysed the clinical and economic burden,...

  • Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus pneumoniae β-galactosidase, BgaA. Singh, Anirudh K.; Pluvinage, Benjamin; Higgins, Melanie A.; Dalia, Ankur B.; Woodiga, Shireen A.; Flynn, Matthew; Lloyd, Audrey R.; Weiser, Jeffrey N.; Stubbs, Keith A.; Boraston, Alisdair B.; King, Samantha J. // PLoS Pathogens;Sep2014, Vol. 10 Issue 9, p1 

    Bacterial cell-surface proteins play integral roles in host-pathogen interactions. These proteins are often architecturally and functionally sophisticated and yet few studies of such proteins involved in host-pathogen interactions have defined the domains or modules required for specific...

  • Epidemiologic Evidence for Serotype-Specific Acquired Immunity to Pneumococcal Carriage. Weinberger, Daniel M.; Dagan, Ron; Givon-Lavi, Noga; Regev-Yochay, Gili; Malley, Richard; Lipsitch, Marc // Journal of Infectious Diseases;6/1/2008, Vol. 197 Issue 11, p1511 

    Nasopharyngeal carriage of Streptococcus pneumoniae is required for transmission of the bacteria and for invasive disease. There have been conflicting reports as to whether protection against carriage is serotype specific and which immune mechanisms drive carriage. Analyzing longitudinal...

  • Bacterial Pneumonia in Children - Epidemiological Study on Nine Years. Chiru, Mirela Luminiţa; Pacurar, Daniela; Oraseanu, D. // Medicina Moderna;2014, Vol. 21 Issue 4, p266 

    Pneumonia is defined as inflammation of the lung parenchyma, affecting the alveolar space. WHO estimated a median incidence of 0.28 episodes of pneumonia worldwide / child / year. This leads to an annual incidence of 150.7 million new cases, of which 11-20000000 (7-13%) are severe requiring...

  • Proportion of Invasive Pneumococcal Infections in German Children Preventable by Pneumococcal Conjugate Vaccines. Von Kries, R &uumi; diger; Siedler, Anette; Schmitt, Heinz J.; Reinert, Ralf Ren é // Clinical Infectious Diseases;8/1/2000, Vol. 31 Issue 2, p482 

    Deals with a study which investigated the incidence and serotype distribution of Streptococcus pneumoniae as a cause of invasive diseases of children in Germany from January 1997 through December 1998. Variation on the magnitude of impact of a conjugate pneumococcal vaccine; Clinical process...

  • Epidemiology of meningitis in Oman, 2000-2005. Dash, N.; Al Khusaiby, S.; Behlim, T.; Mohammadi, A.; Mohammadi, E.; Al Awaidy, S. // Eastern Mediterranean Health Journal;nov/dic2009, Vol. 15 Issue 6, p1358 

    We reviewed the epidemiologic features and trends for 771 cases of meningitis in Oman from January 2000 to December 2005. We found 69% were bacterial in origin and 13% were viral. Leading bacterial pathogens included Haemophilus influenzae (15%), Streptococcus pneumoniae (14%) and Nesseria...

  • The Pneumonia Etiology Research for Child Health Project: A 21st Century Childhood Pneumonia Etiology Study. Levine, Orin S.; O'Brien, Katherine L.; Deloria-Knoll, Maria; Murdoch, David R.; Feikin, Daniel R.; DeLuca, Andrea N.; Driscoll, Amanda J.; Baggett, Henry C.; Brooks, W. Abdullah; Howie, Stephen R. C.; Kotloff, Karen L.; Madhi, Shabir A.; Maloney, Susan A.; Sow, Samba; Thea, Donald M.; Scott, J. Anthony // Clinical Infectious Diseases;2012 Supplement 2, Vol. 54, p93 

    The Pneumonia Etiology Research for Child Health (PERCH) project is a 7-country, standardized, comprehensive evaluation of the etiologic agents causing severe pneumonia in children from developing countries. During previous etiology studies, between one-quarter and one-third of patients failed...

  • A Literature Review and Survey of Childhood Pneumonia Etiology Studies: 2000-2010. Gilani, Zunera; Kwong, Yuenting D.; Levine, Orin S.; Deloria-Knoll, Maria; Scott, J. Anthony G.; O'Brien, Katherine L.; Feikin, Daniel R. // Clinical Infectious Diseases;2012 Supplement 2, Vol. 54, p102 

    The Pneumonia Etiology Research for Child Health (PERCH) project is the largest multicountry etiology study of childhood pneumonia since the Board on Science and Technology in International Development studies of the 1980s. However, it is not the only recent or ongoing pneumonia etiology study,...


Read the Article


Sign out of this library

Other Topics