TITLE

Hyperinsulinism and Beckwith-Wiedemann syndrome

AUTHOR(S)
Munns, C. F.J.; Batch, J. A.
PUB. DATE
January 2001
SOURCE
Archives of Disease in Childhood -- Fetal & Neonatal Edition;Jan2001, Vol. 84 Issue 1, p67
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Beckwith-Wiedemann syndrome (BWS) uncommon cause of neonatal hyperinsulinaemic hypoglycemia. To improve understanding of researchers hypoglycemia in BWS, a comparison of this condition with the more well defined causes of neonatal hyperinsulinism was carried out. The other causes of neonatal hyperinsulinism can be divided into persistent hyperinsulinaemic hypoglycemia of infancy hyperinsulinism hyperammonaemia syndrome and transient hyperinsulinaemic hypoglycemia. There are many similarities between the hyperinsulinaemic hypoglycemia of BWS and other forms of neonatal hyperinsulinism.
ACCESSION #
12949119

 

Related Articles

  • Laparoscopic identification and removal of focal lesions in persistent hyperinsulinemic hypoglycemia of infancy. Bax, N. M. A.; van der Zee, D. C.; de Vroede, M.; Jansen, M.; Nikkels, P. G. J.; Nikkels, J // Surgical Endoscopy;May2003, Vol. 17 Issue 5, p833 

    Background: Persistent hyperinsulinemic hypoglycemia of infancy (PHHI) is a heterogeneous condition. A number of children have focal lesions, and removal of these lesions is curative. However, these lesions are difficult to detect, even during surgery. A laparoscopic approach is...

  • Operational Thresholds in Neonatal Hypoglycemia. Huffman, Grace Brooke // American Family Physician;11/15/2000, Vol. 62 Issue 10, p2322 

    Presents a study by M. Cornblath and others that provides a consensus statement based on neonatal hypoglycemia research data. Description of the study and its results; Conclusion that many questions remain about the effects of hypoglycemia on neonates, although some guidelines can be reasonably...

  • A Trial in Progress: Gestational Diabetes. Rowan, Janet A. // Diabetes Care;Jul2007 Supplement 2, Vol. 30, pS214 

    The article focuses on the Metformin in Gestational Diabetes (MiG) trial in Auckland, New Zealand. It says that this trial was conducted on women with gestational diabetes mellitus (GDM) to test the hypothesis that metformin treatment, compared with insulin, is associated with similar perinatal...

  • A Case of Transient Hypoglycemia and Hyperglycemia in a Full-Term Neonate. Aziz, Ezzat M.; Lipsitz, Philip J. // Clinical Pediatrics;Jun1973, Vol. 12 Issue 6, p363 

    Several cases ot transient diabetes mellitus in newborns have been reported in the literature. We would like to report this instance of transient neonatal hypoglycemia and hyperglycemia because of the unusual onset and course.

  • Clinical Features of 52 Neonates with Hyperinsulinism. de Lonlay-Debeney, Pascale; Poggi-Travert, Florence; Fournet, Jean-Christophe; Sempoux, Christine; Vici, Carlo Dionisi; Brunelle, Francis; Touati, Guy; Rahier, Jacques; Junien, Claudine; Nihoul-Fékété, Claire; Robert, Jean-Jacques; Saudubray, Jean-Marie // New England Journal of Medicine;04/15/99, Vol. 340 Issue 15, p1169 

    Background: Neonatal hyperinsulinemic hypoglycemia is often resistant to medical therapy and is often treated with near-total pancreatectomy. However, the pancreatic lesions may be focal and treatable by partial pancreatic resection. Methods: We studied 52 neonates with hyperinsulinism who were...

  • SELF ASSESSMENT ANSWERS: A hungry baby fails to thrive.  // Postgraduate Medical Journal;Jun2001, Vol. 77 Issue 908, p420 

    Neonatal diabetes differs from insulin dependent diabetes in that it has a highly variable course. About half of these infants have permanent diabetes, and half have a period of remission, although 65% of the transient forms subsequently become diabetic again. The transient and permanent forms...

  • Congenital Hyperinsulinism in Brazilian Neonates: A Study of Histology, KATP Channel Genes, and Proliferation of β Cells. Lovisolo, Silvana M.; Mendonça, Berenice B.; Pinto, Emilia M.; Manna, Thais Della; Saldiva, Paulo Hilário N.; Zerbini, Maria Cláudia N. // Pediatric & Developmental Pathology;Sep/Oct2010, Vol. 13 Issue 5, p375 

    Congenital hyperinsulinism (CHI) is a rare pancreatic bcell disease of neonates, characterized by inappropriate insulin secretion with severe persistent hypoglycemia, with regard to which many questions remain to be answered, despite the important acquisition of its molecular mechanisms in the...

  • A macrosomic newborn with a cystic adrenal mass. Zenker, M.; Schindler, C.; Kändler, C.; Hümmer, H. P.; Rupprecht, T.; Ries, M. // European Journal of Pediatrics;1999, Vol. 158 Issue 3, p261 

    Presents information on the case of an infant diagnosed with Wiedemann-Beckwith syndrome (WBS). Result of physical examination; Characteristic features of WBS.

  • The Causes of Neonatal Hypoglycemia. Stanley, Charles A.; Baker, Lester // New England Journal of Medicine;04/15/99, Vol. 340 Issue 15, p1200 

    Discusses the causes of neonatal hypoglycemia. Importance of the first feeding and the time frame in which it takes place; Developmental immaturity of two of the three mechanisms in the liver that protect against hypoglycemia during fasting; Indications that the genes for the two...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics