Neonatal cerebral infarction and visual function at school age

Mercuri, E.; Anker, S.; Guzzetta, A.; Barnett, A.; Haataja, L.; Rutherford, M.; Cowan, F.; Dubowitz, L.; Braddick, O.; Atkinson, J.
November 2003
Archives of Disease in Childhood -- Fetal & Neonatal Edition;Nov2003, Vol. 88 Issue 6, pF487
Academic Journal
Objective: To assess various aspects of visual function at school age in children with neonatal cerebral infarction. Patients and methods: Sixteen children born at term, who had cerebral infarction of perinatal onset on neonatal magnetic resonance imaging (MRI) were assessed using a battery of visual tests. This included measures of crowding acuity (Cambridge Crowding Cords), stereopsis (TNO test), and visual fields. The results of the visual assessment were compared with the type and the extent of the lesion observed on neonatal MRI. Results: Only six of the 16 children (28%) had some abnormalities of visual function on these tests. Visual abnormalities were more common in children with more extensive lesions involving the main branch of the middle cerebral artery and were less often associated with lesions in the territory of one of the cortical branches of the middle cerebral artery. The presence of visual abnormalities was not always associated with the involvement of optic radiations or occipital primary visual cortex. Abnormal visual fields were only found in children who also developed hemiplegia. Conclusions: Abnormality of visual function is not common in children who had neonatal infarction and, when present, tends to be associated with hemiplegia and more extensive lesions.


Related Articles

  • WebParc: a tool for analysis of the topography and volume of stroke from MRI. Kennedy, David N.; Haselgrove, Christian; Makris, Nikos; Goldin, Donald M.; Lev, Michael H.; Caplan, David; Caviness, Verne S. // Medical & Biological Engineering & Computing;Mar2010, Vol. 48 Issue 3, p215 

    The quantitative assessment of the anatomic consequences of cerebral infarction is critical in the study of the etiology and therapeutic response in patients with stroke. We present here an overview of the operation of “WebParc,” a computational system that provides measures of...

  • Evolution of the diffusion-weighted signal and the apparent diffusion coefficient in the late phase after minor stroke. Schulz, U. G. R.; Flossmann, E.; Francis, J. M.; Redgrave, J. N.; Rothwell, P. M. // Journal of Neurology;Mar2007, Vol. 254 Issue 3, p375 

    Diffusion-weighted imaging (DWI) is mainly used in acute stroke, and signal evolution in the acute phase has been studied extensively. However, patients with a minor stroke frequently present late. Recent studies suggest that DWI may be helpful at this stage, but only very few published data...

  • Bilateral symmetric junctional infarctions of the cerebellum: a case report. Kiroğlu, Yılmaz; Karabulut, Nevzat; Oncel, Cagatay; Akdogan, Ilgaz; Onur, Sule // Surgical & Radiologic Anatomy;Jun2010, Vol. 32 Issue 5, p509 

    The advances in neuroimaging have improved clinicoanatomic correlations in patients with stroke. Junctional infarct is a distinct term, used to describe border zone infarcts of the posterior fossa. We presented computed tomography (CT) and magnetic resonance imaging (MRI) findings in a rare case...

  • Stroke Subtypes on Imaging in a Jamaican Population A Hospital-based Study. West, W. M.; Younger, N.; Brady-West, D.; Gilbert, D. T.; Char, G.; Barton, E. N. // West Indian Medical Journal;Jun2009, Vol. 58 Issue 3, p261 

    Objective: To examine the pattern of stroke subtypes found on Computed Tomography (CT), Magnetic Resonance Imaging (MRI) at the University Hospital of the West Indies (UHWI), Kingston, Jamaica. Method: A retrospective review was conducted for all patients diagnosed with stroke and who were...

  • RNase Therapy Assessed by Magnetic Resonance Imaging Reduces Cerebral Edema and Infarction Size in Acute Stroke. Walberer, Maureen; Tschernatsch, Marlene; Fischer, Silvia; Ritschel, Nouha; Volk, Kai; Friedrich, Carolin; Bachmann, Georg; Mueller, Clemens; Kaps, Manfred; Nedelmann, Max; Blaes, Franz; Preissner, Klaus T.; Gerriets, Tibo // Current Neurovascular Research;Feb2009, Vol. 6 Issue 1, p12 

    Ischemic stroke causes cell necrosis with the exposure of extracellular ribonucleic acid (RNA) and other intracellular material. As shown recently, extracellular RNA impaired the blood-brain-barrier and contributed to vasogenic edema-formation. Application of ribonuclease 1 (RNase 1) diminished...

  • Free radical scavenger, edaravone, reduces the lesion size of lacunar infarction in human brain ischemic stroke. Nakase, Taizen; Yoshioka, Shotaroh; Suzuki, Akifumi // BMC Neurology;2011, Vol. 11 Issue 1, p39 

    Background: Although free radicals have been reported to play a role in the expansion of ischemic brain lesions, the effect of free radical scavengers is still under debate. In this study, the temporal profile of ischemic stroke lesion sizes was assessed for more than one year to evaluate the...

  • The Role of Multidetector CT Venography in Diagnosis of Cerebral Venous Sinus Thrombosis. Mahmoud, Mohamed Abdel Latif; Elbeblawy, Moataz Mohamed Samy // Research Journal of Medicine & Medical Sciences;2009, Vol. 4 Issue 2, p284 

    Cerebral venous thrombosis is a disorder that is challenging to diagnose. The diagnostic difficulty results in large part from the wide variety of clinical manifestations of this uncommon disorder. Twenty patients were diagnosed as having cerebral sinovenous thrombosis on CT venography were...

  • The Application of Diffusion- and Perfusion-Weighted Magnetic Resonance Imaging in the Diagnosis and Therapy of Acute Cerebral Infarction. Ying Han; Enzhong Li; Jie Tian; Jian Chen; Huifang Wang; Jianping Dai // International Journal of Biomedical Imaging;2006, p1 

    Diffusion- and perfusion-weighted magnetic resonance imaging (DWI and PWI) was applied for stroke diagnose in 120 acute (< 48 h) ischemic stroke patients. At hyperacute (< 6 h) stage, it is difficult to find out the infarction zone in conventional T1 or T2 image, but it is easy in DWI, apparent...

  • Sensitivity of the Neuroimaging Techniques in Ischemic Stroke. Smajlovic, Dzevdet; Sinanovic, Osman // Acta Informatica Medica;2006, Vol. 14 Issue 1, p16 

    The aim of this study was to investigate and compare the sensitivity and effectiveness of neuroimaging techniques in 190 patients with acute ischemic stroke. The first computed tomography (CT) scan for all patients was performed within the first 12 hours of the stroke symptoms onset. For each...


Read the Article


Sign out of this library

Other Topics