TITLE

Neonatal thrombocytosis resulting from the maternal use of non-narcotic antischizophrenic drugs during pregnancy

AUTHOR(S)
Nako, Y.; Tachibana, A.; Fujiu, T.; Tomomasa, T.; Morikawa, A.
PUB. DATE
May 2001
SOURCE
Archives of Disease in Childhood -- Fetal & Neonatal Edition;May2001, Vol. 84 Issue 3, pF198
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Neonatal thrombocytosis can result from maternal narcotic drug abuse. The case of a male infant is reported who was born to a woman with schizophrenia treated with non-narcotic psychotropic drugs during pregnancy; he developed severe prolonged thrombocytosis. The platelet count reached 1310×109/l on day 15. This thrombocytosis persisted for three months. The patient was treated with dipyridamole. A bone marrow aspirate showed normal myeloid and erythroid precursors with an increased number of megakaryocytes. Plasma concentrations of interleukin 6 and thrombopoietin were suppressed. No obvious complications from the thrombocytosis occurred, and the platelet count fell to within the upper limit of normal after 3 months of age. This case indicates that thrombocytosis may occur in infants born to mothers treated with non-narcotic psychopharmaceutical drugs during pregnancy. The thrombocytosis in this case may have been induced by factors other than interleukin 6 or thrombopoietin.
ACCESSION #
12949015

 

Related Articles

  • Sulpiride Augmentation of Olanzapine in Treatment -- Resistant Schizophrenia.  // Child & Adolescent Psychopharmacology News;2004, Vol. 9 Issue 2, p11 

    The article presents information about a study on the management of treatment-resistant schizophrenia by sulpiride augmentation of olanzapine in patients published in an issue of "International Clinical Psychopharmacology." This study involved seventeen patients with chronic schizophrenia. The...

  • Benzodiazepines implicated in preterm birth.  // Reactions Weekly;4/24/2010, Issue 1298, p1 

    The article presents the study "Risk of Preterm Delivery and Other Adverse Perinatal Outcomes in Relation to Maternal Use of Psychotropic Medications During Pregnancy," by R. Calderon-Margalit et al, published in the December 2009 issue of "American Journal of Obstetrics and Gynecology."

  • Small bowel perforation in the premature neonate: congenital or acquired? Holland, A. J. A.; Shun, A.; Martin, H. C. O.; Cooke-Yarborough, C.; Holland, J. // Pediatric Surgery International;Aug2003, Vol. 19 Issue 6, p489 

    To determine the potential aetiological factors of small bowel perforation in the premature neonate, we performed a retrospective chart review of those neonates with spontaneous intestinal perforation (SIP) of the small bowel seen in our tertiary paediatric hospital between January 1980 and...

  • Small bowel perforation in the premature neonate: congenital or acquired? Holland, A. J. A.; Shun, A.; Martin, H. C. O.; Cooke-Yarborough, C.; Holland, J. // Pediatric Surgery International;Aug2003, Vol. 19 Issue 6, p489 

    To determine the potential aetiological factors of small bowel perforation in the premature neonate, we performed a retrospective chart review of those neonates with spontaneous intestinal perforation (SIP) of the small bowel seen in our tertiary paediatric hospital between January 1980 and...

  • Small bowel perforation in the premature neonate: congenital or acquired? Holland, A. J. A.; Shun, A.; Martin, H. C. O.; Cooke-Yarborough, C.; Holland, J. // Pediatric Surgery International;Aug2003, Vol. 19 Issue 6, p489 

    To determine the potential aetiological factors of small bowel perforation in the premature neonate, we performed a retrospective chart review of those neonates with spontaneous intestinal perforation (SIP) of the small bowel seen in our tertiary paediatric hospital between January 1980 and...

  • Amphetamine abuse in pregnancy: the impact on obstetric outcome. Phupong, Vorapong; Darojn, Darigar // Archives of Gynecology & Obstetrics;Sep2007, Vol. 276 Issue 2, p167 

    To determine whether pregnant women with amphetamine abuse developed more obstetric complications than non-drug abuser pregnant women. A retrospective case control study was undertaken. Pregnant women with amphetamine abuse who delivered between January 2002 and December 2003 were compared to...

  • Use of Antipsychotics in the Management of Schizophrenia during Pregnancy. Trixler, Mátyás; Gáti, Ágnes; Fekete, Sándor; Tényi, Tamás // Drugs;2005, Vol. 65 Issue 9, p1193 

    The rapid development of pharmacotherapy has resulted in a growing clinical importance for the treatment of the increasing number of women with schizophrenia during pregnancy. An evolving database on reproductive health safety factors for women with schizophrenia has begun to be of assistance in...

  • Safety and efficacy of early amino acids in preterm <28 weeks gestation: prospective observational comparison. Kotsopoulos, K.; Benadiba-Torch, A.; Cuddy, A.; Shah, P. S. // Journal of Perinatology;Dec2006, Vol. 26 Issue 12, p749 

    Objective:To assess the safety and efficacy of early amino acid (AA) administration in preterm neonates <28 weeks gestational age.Study design:Prospective data collection for 1 year for the late AA group (AA started at 12–30 h) and for another year with practice change to early AA...

  • Neonatal Seizures following Lidocaine Administration for Elective Circumcision. Moran, Lisa R.; Hossain, Tanzeema; Insoft, Robert M. // Journal of Perinatology;Jun2004, Vol. 24 Issue 6, p395 

    We report a case of a 25-day old, former 34-week gestation male newborn who experienced neonatal seizures following administration of subcutaneous lidocaine for regional anesthesia during an elective circumcision prior to discharge.Journal of Perinatology (2004) 24, 395-396....

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics