High or low oxygen saturation for the preterm baby

Mcintosh, Neil
May 2001
Archives of Disease in Childhood -- Fetal & Neonatal Edition;May2001, Vol. 84 Issue 3, pF149
Academic Journal
The observational study by several researchers of outcome related to oxygen saturation in infants of less than 28 weeks gestation from a number of disparate units in Great Britain shows results that are interesting, but only from the point of hypothesis generation. Monitoring of oxygen saturation is simple but not without problems. Setting aside whether preterm infants requiring additional oxygen should be managed by monitoring oxygen saturation or oxygen partial pressure, does this study have any implications for management of such infants in the future? Is there any other corroborative evidence that the outcome of infants managed at lower saturations do better in terms of neurodevelopmental, respiratory, growth, or visual outcome? The study was designed to test the hypothesis that supplemental oxygen would reduce progression of retinopathy of prematurity.


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