LUNG ALERT: Non-linear relationship between lung cancer risk and cigarette tar yield

Davis, H. E.
April 2004
Thorax;Apr2004, Vol. 59 Issue 4, p354
Academic Journal
This study was undertaken to determine the risk of lung cancer associated with medium, low, and very low tar filter cigarettes. Using a cohort of patients from the US cancer prevention study II (CPS-II), 364 239 men (100 868 current smokers) and 576 535 women (124 270 current smokers) were studied. The primary outcome measure was death from tracheal or lung cancer over 6 years of follow up. The risk of lung cancer was increased in current smokers, with high tar cigarette smokers experiencing the highest risk. No difference was evident between the medium, low, and very low tar brands. These results withstood sensitivity analysis, including exclusion of people with smoking related diseases.


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