Parental smoking in childhood and adult obstructive lung disease: results from the European Community Respiratory Health Survey

Svanes, C.; Omenaas, E.; Jarvis, D.; Chinn, S.; Gulsvik, A.; Burney, P.
April 2004
Thorax;Apr2004, Vol. 59 Issue 4, p295
Academic Journal
journal article
Background: Early exposure to parental smoking appears to influence the development of the airways and predispose to respiratory symptoms, A study was undertaken to determine whether the consequences of parental smoking could be traced in adulthood. Methods: Information from interviewer-led questionnaires was available for 18 922 subjects aged 20- 44 years from random population samples in 37 areas participating in the European Community Respiratory Health Survey. Lung function data were available for 15 901 subjects. Results: In men, father's smoking in childhood was associated with more respiratory symptoms (ORwheeze 1.13 (95% Cl 1.00 to 1.28); never smokers: ORwheeze 1.21(95% Cl 0.96 to 1.50)) and there was a dose- dependent association between number of parents smoking and wheeze (one: OR 1.08 (95% Cl 0.94 to 1.24); both: OR 1.24(95% CI 1.05 to 1.47); Ptrend = 0.010). A reduced ratio of forced expiratory volume in 1 second (FEV1) to forced vital capacity (FVC) was related to father's smoking (-0.3% (95% Cl -0.6 to 0)) and number of parents smoking (Ptrend <0.001) among men. In women, mother's smoking was associated with more respiratory symptoms and poorer lung function (ORwheeze 1.15 (95% Cl 1.01 to 1.31), never smokers: ORwheeze 1.21(95% Cl 0.98-1.51); FEV1 -24 ml (95% CI -45 to -3); FEV1/FVC ratio -0.6% (95% Cl -0.9 to -0.3)). These effects were possibly accounted for by maternal smoking in pregnancy (ORwheeze 1.39 (95% Cl 1.17 to 1.65); FEV1 -23 ml (95% Cl -52 to 7); FEV1/FYC ratio -0.9% (95% Cl -1.3 to -0.4)) as there was no association with paternal smoking among women (interaction by sex, p<0.05). These results were homogeneous across centres. Conclusion: Both intrauterine and environmental exposure to parental tobacco smoking was related to more respiratory symptoms and poorer lung function in adulthood in this multicultural study. The age window of particular vulnerability appeared to differ by sex, postnatal exposure being important only in men and a role for prenatal exposure being more evident in women.


Related Articles

  • Effects of parental smoking on the respiratory health of adults. Upton, M. N. // Thorax;Apr2004, Vol. 59 Issue 4, p274 

    The article reports the effects of parental smoking on the respiratory health of adults. C. Svanes and colleagues take a short cut and report cross-sectional results from the European Community Respiratory Health Survey (ECRHS) linking recalled information about parental smoking to respiratory...

  • CLINICAL CLIPS. Pohl, Charles A.; Mintz, Matthew; Russell, John J. // Patient Care for the Nurse Practitioner;Aug2007, Vol. 10 Issue 8, p12 

    The article discusses several studies on antibiotic choices for chronic bronchitis. A meta-analysis revealed no differences regarding treatment success among macrolides and quinolones, amoxicillin/clavulanate (A/C) and quinolones, or A/C and macrolides. Another research found that maternal...

  • Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among children in Taiwan. Ching-Hui Tsai; Jiun-Hau Huang; Bing-Fang Hwang; Yungling L. Lee // Respiratory Research;2010, Vol. 11, p1 

    Background: Although studies show that maternal smoking during pregnancy increases the risks of respiratory outcomes in childhood, evidence concerning the effects of household environmental tobacco smoke (ETS) exposure remains inconsistent. Methods: We conducted a population-based study...

  • Research Briefs: Pregnant smokers.  // GP: General Practitioner;9/5/2012, p12 

    The article reports that researchers from Sweden say that pregnant women who smoke increase their child's risk of developing asthma and wheezing.

  • Intrauterine Cocaine, Lead and Nicotine Exposure and Fetal Growth. Neuspiel, Daniel R.; Markowitz, Morri; Drucker, Ernest // American Journal of Public Health;Sep94, Vol. 84 Issue 9, p1492 

    Intrauterine tobacco, lead, and cocaine exposure often co-occur and may affect fetal growth and development, yet studies of gestational cocaine effects have not adequately measured lead or tobacco. In this anonymous survey, blood lead and urine cotinine levels were determined and mothers were...

  • Supporting pregnant women to quit smoking -- a critique.  // Midwifery News;Jun2008, Issue 49, p39 

    The article presents information on a research conducted to find the role of midwives and general practitioners in helping pregnant women from New Zealand to quit smoking. 98% of the midwives said that they check for smoking status in the records of their patients. 80% of the midwives advised...

  • Quick guide to... Smoking while pregnant.  // Children & Young People Now (Haymarket Business Publications Ltd;2/5/2009, p25 

    The article presents survey about smoking during pregnancy in Great Britain in 2005. Survey shows that around a third of women smoke before pregnancy. However, about half of them manage to stop when they become pregnant. It was found out that the babies born to women who smoke are on average 200...

  • Maternal cigarette smoking and its effect on neonatal lymphocyte subpopulations and replication. Almanzar, Giovanni; Eberle, Gernot; Lassacher, Andrea; Specht, Christian; Koppelstaetter, Christian; Heinz-Erian, Peter; Traw√∂ger, Rudolf; Bernhard, David; Prelog, Martina // BMC Pediatrics;2013, Vol. 13 Issue 1, p1 

    Background: Significant immunomodulatory effects have been described as result of cigarette smoking in adults and pregnant women. However, the effect of cigarette smoking during pregnancy on the lymphocyte subpopulations in newborns has been discussed, controversially. Methods: In a prospective...

  • Gender effects of reported in utero tobacco exposure on smoking initiation, progression and nicotine dependence in adult offspring. Oncken, Cheryl; McKee, Sherry; Krishnan-Sarin, Suchitra; O'Malley, Stephanie; Mazure, Carolyn // Nicotine & Tobacco Research;Oct2004, Vol. 6 Issue 5, p829 

    We examined the relationship between self-reported in utero tobacco exposure and gender on smoking initiation, progression of cigarette use (i.e., telescoping), and current levels of nicotine dependence in adult treatment-seeking smokers. Subjects (N= 298) who reported "yes" (28% of the original...


Read the Article


Sign out of this library

Other Topics