Prevalence of untreated asthma in a population sample of 6000 older adults in Bristol, UK

Dow, L.; Fowler, L.; Phelps, L.; Waters, K.; Coggon, D.; Kinmonth, A. L.; Holgate, S. T.
June 2001
Thorax;Jun2001, Vol. 56 Issue 6, p472
Academic Journal
Background-A study was undertaken to estimate the prevalence of untreated asthma in older adults. Methods-A cross sectional population based survey of 6000 men and women aged 65 years and over was performed in 21 general practices in north Bristol, south west England. The main outcome measure was untreated asthma as defined by a two stage process comprising a respiratory questionnaire (symptoms suggestive of asthma or doctor diagnosed asthma not receiving respiratory treatment) followed by lung function tests (significant reversibility following bronchodilators or corticosteroids and/or significant within day variability in peak expiratory flow). Results-4792 of the 6000 participants (80%) completed the respiratory questionnaire and, of those not receiving respiratory treatment, 55 reported a previous doctor diagnosis of asthma and a further 696 had symptoms suggestive of asthma. Lung function testing in 280 of 501 randomly selected individuals from these groups resulted in 38 being defined as having asthma and an estimated population prevalence for untreated asthma of 2.4% (95% CI 1.6% to 3.6%) in men and 1.2% (95% CI 0.7% to 2.1%) in women. Most subjects (84%) with untreated asthma had moderate or severe disease. Untreated asthma was most common in individuals with doctor diagnosed asthma (21%) and those with breathlessness or wheeze (13-20%). Conclusion-Untreated asthma in the elderly is a common and important problem. Opportunistic use of appropriate lung function tests in older people with a history of doctor diagnosed asthma or wheeze or breathlessness at rest could identify untreated asthmatics who might benefit from treatment.


Related Articles

  • COMPLICATED BRONCHIAL ASTHMA.  // Cortlandt Forum;06/25/2001, Vol. 14 Issue 6, p83 

    Answers queries on complicated bronchial asthma of patients with restrictive component on pulmonary function testing in Lorain County, Ohio. Causes of the asthma; Determination on the relation between obstructive and restrictive components; Evaluation of lung disease.

  • Two patients with occupational asthma who returned to work with dust respirators. Obase, Yasushi; Shimoda, Terufumi; Mitsuta, Kazuko; Matsuse, Hiroto; Kohno, Shigeru // Occupational & Environmental Medicine;Jan2000, Vol. 57 Issue 1, p62 

    Objectives: To assess the efficacy of dust respirators in preventing asthma attacks in patients with occupational asthma (asthma induced by buckwheat flour or wheat flour). Methods: The effect of the work environment was examined in two patients with occupational asthma with and without the use...

  • Asthma and chronic obstructive pulmonary disease: differences between workers with and without sick leave. Boot, C. R. L.; van der Gulden, J. W. J.; Orbon, K. H.; Vercoulen, J. H. M. M.; Akkermans, R.; van Weel, C.; Folgering, H. T. M. // International Archives of Occupational & Environmental Health;Jun2004, Vol. 77 Issue 5, p357 

    Objective: Determinants of sick leave should be investigated before interventions to reduce sick leave can be designed. This cross-sectional study compares employees with asthma and chronic obstructive pulmonary disease (COPD) with and without sick leave. Methods: One hundred and eighteen...

  • ALLERGEN EXPOSURE AND THE DEVELOPMENT OF ASTHMA. Sporik, R.; Platts-Mills, T. A. E. // Thorax;Sep2001 Supp, Vol. 56, pii58 

    Background: In a prospective birth cohort study, we assessed the relevance of mite and cat allergen exposure for the development of childhood asthma up to age 7 years. Methods: Of 1314 newborn infants enrolled in five German cities in 1990, follow-up data at age 7 years were available for 939...

  • Role of forced expiratory flow at 25–75% as an early marker of small airways impairment in subjects with allergic rhinitis. Marseglia, Gian Luigi; Cirillo, Ignazio; Vizzaccaro, Andrea; Klersy, Catherine; Tosca, Maria Angela; La Rosa, Mario; Marseglia, Alessia; Licari, Amelia; Leone, Maddalena; Ciprandi, Giorgio // Allergy & Asthma Proceedings;Jan/Feb2007, Vol. 28 Issue 1, p74 

    A close link exists between allergic rhinitis and asthma. Small airway disease (SAD), defined by a reduction in forced expiratory flow at 25–75% of the pulmonary volume (FEF25–75) and normal spirometry (normal forced expiratory volume at 1 second [FEV1], forced vital capacity...

  • Accuracy of asthma and COPD diagnosis in Australian general practice: a mixed methods study. Abramson, Michael J.; Schattner, Rosa L.; Sulaiman, Nabil D.; Del Colle, Eleonora A.; Aroni, Rosalie; Thien, Francis // Primary Care Respiratory Journal;Jun2012, Vol. 21 Issue 2, p167 

    Background: Spirometry is the 'gold standard' for diagnosing asthma and chronic obstructive pulmonary disease (COPD) but is rarely used in general practice. Aims: To compare doctor diagnoses with patient reports/spirometry and to determine doctors' perceptions of spirometry. Methods: Patients...

  • Prevalence of Exercise Induced Asthma in Female School Students. Marefati, Hamid; Nikbine, Helimeh; Boskabady, Mohammad Hossein // Iranian Journal of Allergy, Asthma & Immunology;2011, Vol. 10 Issue 4, p273 

    The prevalence of exercise induced asthma (EIA) in Iran is not known. In the present study the prevalence of EIA among female students of guidance school in the city of Mashhad was evaluated. A total of 1690 female students aged 12-14 years in ten randomly selected schools in north east of Iran...

  • Impulse oscillometry: an alternative modality to the conventional pulmonary function test to categorise obstructive pulmonary disorders. Al-Mutairi, S.; Sharma, P.; Al-Alawi, A.; Al-Deen, J. // Clinical & Experimental Medicine;Jun2007, Vol. 7 Issue 2, p56 

    Impulse oscillometry (IOS) was introduced as an alternative modality to the conventional pulmonary function test (cPFT) to test lung mechanics. The objective of this study is to assess the use of IOS as an alternative, or in conjunction with cPFT, to categorise an obstructive respiratory...

  • Current pattern of spirometry utilisation in a sub-Saharan African country. Nwosu, N. I.; Chukwuka, C. J.; Onyedum, C. C.; Odilinye, H. C.; Nlewedim, P. I.; Ayuk, A. C. // African Journal of Respiratory Medicine;Sep2016, Vol. 12 Issue 1, p15 

    Spirometry is recommended in the assessment of respiratory diseases. It was however reported to be underutilised in Nigeria. This study assessed current patterns in spirometry utilisation in terms of frequency and sources of referral, the indications for referral and patterns of ventilatory...


Read the Article


Sign out of this library

Other Topics