Bilirubin inhibits bile acid induced apoptosis in rat hepatocytes
- Water-soluble component of the antioxidant system under the conditions of 520-day isolation. Morukov, B.; Popov, I.; Levin, G.; Markin, A.; Zhuravleva, O.; Kuzichkin, D. // Human Physiology;Dec2015, Vol. 41 Issue 7, p808
In this study, which was carried out as part of the Mars-500 international project, six men at the age of 28 to 39 years were isolated in a pressure chamber for 520 days. Their parameters of the antioxidant system, including concentration of bilirubin, uric acid, and the total antioxidant...
- Protective Role of Morin, a Flavonoid, against High Glucose Induced Oxidative Stress Mediated Apoptosis in Primary Rat Hepatocytes. Kapoor, Radhika; Kakkar, Poonam; Gallyas, Ferenc // PLoS ONE;Aug2012, Vol. 7 Issue 8, Special section p1
Apoptosis is an early event of liver damage in diabetes and oxidative stress has been linked to accelerate the apoptosis in hepatocytes. Therefore, the compounds that can scavenge ROS may confer regulatory effects on high- glucose induced apoptosis. In the present study, primary rat...
- Higher serum total bilirubin concentration is associated with lower risk of renal insufficiency in an adult population. Ang-Tse Lee; Ya-Yu Wang; Shih-Yi Lin; Jiin-Tsae Liang; Wayne Huey-Herng Sheu; Yuh-Min Song; Wen-Dau Chang // International Journal of Clinical & Experimental Medicine;2015, Vol. 8 Issue 10, p19212
Background: Chronic inflammation is proposed to play a central role in the pathogenesis of chronic kidney disease (CKD), and serum bilirubin has antioxidant and anti-inflammatory effects. We investigated the association between serum total bilirubin (Tb) concentration and renal function in an...
- urobilinogen. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p2416
A definition of the medical term "urobilinogen" is presented, which refers to a colorless derivative of bilirubin.
- bilirubin. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p261
The definition of the term "bilirubin," which refers to the orange-colored or yellowish pigment in bile, is presented.
- bilirubinate. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p262
The definition of the term "bilirubinate," which refers to a salt of bilirubin, is presented.
- biliuria. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p262
The definition of the term "biliuria," which refers to bilirubinuria, is presented.
- biliverdin. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p262
The definition of the term "biliverdin," which refers to the greenish pigment in bile formed by the oxidation of bilirubin, is presented.
- Biddable death. Nagata, Shigekazu // Nature Cell Biology;Oct99, Vol. 1 Issue 6, pE143
Mice lacking the pro-apototic protein Bid are resistant to the lethal effects of 'death-factor' signals relayed through Fas. But whereas Bid-deficient hepatocytes are resistant to Fas-mediated apoptosis, thymocytes and embryonal fibroblasts are not. This confirms the cell-type specificity of the...