From comic relief to real understanding; how intestinal gas causes symptoms

Quigley, E. M. M.
December 2003
Gut;Dec2003, Vol. 52 Issue 12, p1659
Academic Journal
Gas content and transit appear to conspire with the motor and sensory responses of the gut to produce gas related symptoms, both in normal individuals and especially in irritable bowel syndrome (IBS) patients. Gas retention in the small intestine, an organ poorly prepared for this event, is more likely to cause symptoms, especially in an individual who exhibits visceral hypersensitivity. The studies indicate that distension is a real phenomenon in lBS and that such distension accurately reflects gas content. More problematic is extrapolation of the observations relating symptoms to gas transit and retention.


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