TITLE

Body mass, fat percentage, and fat free mass as reference variables for lung function: effects on terms for age and sex

AUTHOR(S)
Cotes, J. E.; Chinn, D. J.; Reed, J. W.
PUB. DATE
November 2001
SOURCE
Thorax;Nov2001, Vol. 56 Issue 11, p839
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background--Sex specific cross sectional reference values for lung function indices usually employ a linear model with terms for age and stature. The effects of also matching for body mass index (BMI = mass/stature²) or its components, fat percentage of body mass (fat%) and fat free mass index (FFMI = fat free mass/stature²) were studied. Methods--The subjects were 458 asymptomatic male and female non-smokers (383 men) and 22 female ex-smokers. Measurements were made of ventilatory capacity, lung volumes, transfer factor (diffusing capacity, single breath CO method), and body composition (skinfold method). Linear and proportional regression models were used. Results--Terms for fat% and FFMI significantly improved the accuracy of reference values for all the primary lung function indices. The improvements in subjects with atypical physiques (fat% and FMI at the ends of the distributions for the subjects) were in the range 0.3-2.3 SD compared with conventional regression equations. The new partial regression coefficients on age were independent of age related changes in body fat. The coefficient for total lung capacity (TLC) on age in men was now positive. Most differences between the sexes were eliminated. A term for BMI improved the descriptions of subdivisions of TLC but lacked the other advantages. Conclusion--Allowance for fat% and FFMI increases the accuracy of reference equations for lung function, particularly for subjects with a lot of fat and little muscle or vice versa. Allowance for BMI is less informative.
ACCESSION #
12915313

 

Related Articles

  • The influence of fat mass on fat-free mass in healthy adults. Burton, R. F. // International Journal of Body Composition Research;2010, Vol. 8 Issue 4, p109 

    Background: Fat-free mass (FFM) tends to vary in response to changing fat mass (FM). Values of typical (positive) ratios ?FFM/?FM (where ? indicates a change or difference) are necessary for understanding the physiological mechanisms and the quantitative relationships amongst FM, body mass and...

  • Nonspecific Pattern of Pulmonary Function Is a Clinical Entity.  // Pulmonary Reviews;May2011, Vol. 16 Issue 5, p23 

    The article reviews the article "The nonspecific pulmonary function test: longitudinal follow-up and outcomes," by V. N. Iyer, D. R. Schroeder and K. O. Parker which appeared in the April 2011 issue of "Chest."

  • Rate of progression of CT-quantified emphysema in male current and ex-smokers: a follow-up study. Hoesein, Firdaus A. A. Mohamed; Zanen, Pieter; de Jong, Pim A.; Ginneken, Bram van; Boezen, H. Marike; Groen, Harry J. M.; Oudkerk, Mathijs; de Koning, Harry J.; Postma, Dirkje S.; Lammers, Jan-Willem J. // Respiratory Research;May2013, Vol. 14 Issue 5, p1 

    Background: Little is known about the factors associated with CT-quantified emphysema progression in heavy smokers. The objective of this study was to investigate the effect of length of smoking cessation and clinical / demographical factors on the rate of emphysema progression and FEV1-decline...

  • Association Between Lung Function and Metabolic Syndrome Independent of Insulin in Japanese Men and Women. Yayoi Yamamoto; Junko Oya; Tomoko Nakagami; Yasuko Uchigata // Japanese Clinical Medicine;2014, Issue 5, p1 

    PURPOSE: We examined the cross-sectional association between lung function and metabolic syndrome (MetS), independent of fasting immunoreactive insulin (F-IRI). METHODS: A total of 3,072 middle-aged, apparently healthy subjects who participated in a general health check-up were included. Lung...

  • Unexpected Smoking-Linked High MMP-9 in Induced Sputum of Hazardous Dust-Exposed Workers. Lerman, Yehuda; Moscovich, Abraham; Fireman, Elizabeth // Mediators of Inflammation;6/1/2006, Vol. 2006 Issue 3, p1 

    We investigated whether metalloproteinase-9 (MMP-9) values in induced sputum (IS) and pulmonary function tests can serve as a marker of damage and intensity of exposure to hazardous dust. Thirty-nine factory employees (28 workers exposed to metal particles and 11 supposedly nonexposed office...

  • Pulmonary Function Measures as Predictors and Correlates of Cognitive Functioning in Later Life. Chyou, Po-Huang; White, Lon R.; Yano, Katsuhiko; Sharp, Dan S.; Burchfiel, Cecil M.; Chen, Randi; Rodriguez, Beatriz L.; Curb, J.David // American Journal of Epidemiology;1996, Vol. 143 Issue 8, p750 

    The relation between pulmonary function and cognitive functioning was investigated in a cohort of 3,036 Japanese-American men living in Hawaii. Pulmonary function, as indicated by forced expiratory volume in 1 second (FEV1), was measured at the baseline examination from 1965 to 1968. Cognitive...

  • Predicting maximum voluntary ventilation in normal healthy individuals using indirect inspiratory muscle strength measurements: a correlation study. Sontakke, Rohit; Deore, Mangesh; Kothari, Dhara // Engineering;Apr2010, Vol. 2 Issue 4, p295 

    Maximum Voluntary Ventilation (MVV), one of the components of Pulmonary Function Testing (PFT), has multiple uses. Various factors including the inspiratory muscle strength (IMS) influence its magnitude. Our aim was to quantify the IMS indirectly using an economical and non invasive bedside...

  • Logistic Regression Model for Prediction of Airway Reversibility Using Peak Expiratory Flow. Shakeri, Javad; Paknejad, Omalbanin; Moghadam, Keivan Gohari; Taherzadeh, Maryam // Tanaffos;2012, Vol. 11 Issue 1, p49 

    Background: Using peak expiratory flow (PEF) as an alternative to spirometry parameters (FEV1 and FVC), for detection of airway reversibility in diseases with airflow limitation is challenging. We developed logistic regression (LR) model to discriminate bronchodilator responsiveness (BDR) and...

  • The Changes of Pulmonary Function in COPD During Four-Year Period. Cukic, Vesna; Lovre, Vladimir; Ustamujic, Aida // Materia Socio Medica;2013, Vol. 25 Issue 2, p88 

    Introduction: COPD (chronic obstructive pulmonary disease) is characterized by airflow limitation that is not fully reversible. OBJECTIVE: to show the changes of pulmonary function in COPD during the 4 -year evolution of illness. Material and Methods: The research was done on patients suffering...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics