TITLE

Women with cystic fibrosis and their potential for reproduction

AUTHOR(S)
Edenborough, F. P.
PUB. DATE
August 2001
SOURCE
Thorax;Aug2001, Vol. 56 Issue 8, p649
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
While it has long been appreciated that up to 98% of men with cystic fibrosis (CF) are infertile due to a failure to develop, or early blockage of, the mesonephric ducts and vas deferens, the effect of CF on the fertility of women is less clear. Survival is now into the fourth decade of life and, with the largest growth in the CF population seen in the adult age groups, it is not surprising that the issues of fertility and reproduction are increasingly raised in adult clinics. Pregnancy is possible and increasing numbers of children are born to women with CF each year. Since the first pregnancy in 1960, management of all aspects of CF has improved and so the prognosis for mother and child has also improved. This paper reviews the pathophysiology of CF in the female reproductive tract, its effect on fertility and the ability to carry a pregnancy, and the outcome for mother and infant.
ACCESSION #
12915279

 

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