Preventing cholesterol absorption
- A dual approach to LDL-C Management. // Managed Healthcare Executive;Jul2004, Vol. 14 Issue 7, p38
Reports on the treatment approach to the management of hyperlipidemia. Functions of the liver in regulating cholesterol balance; Reduction in plasma cholesterol; Importance of the production pathway and the intestinal absorption pathway in the regulation of cholesterol metabolism.
- The effect of cholesteryl ester transfer protein overexpression and inhibition on reverse cholesterol transport. Tchoua, Urbain; D'Souza, Wilissa; Mukhamedova, Nigora; Blum, Denise; Niesor, Eric; Mizrahi, Jacques; Maugeais, Cyrille; Sviridov, Dmitri // Cardiovascular Research;Mar2008, Vol. 77 Issue 4, p732
Aims: Cholesteryl ester transfer protein (CETP) has a well-established role in lipoprotein metabolism, but the effect of its overexpression or inhibition on the efficiency of reverse cholesterol transport (RCT) is unclear.
- Identification of a Novel Hypocholesterolemic Protein, Major Royal Jelly Protein 1, Derived from Royal Jelly. Kashima, Yuri; Kanematsu, Satoshi; Asai, Saori; Kusada, Mio; Watanabe, Suzuyo; Kawashima, Takuji; Nakamura, Tadashi; Shimada, Masaya; Goto, Tsuyoshi; Nagaoka, Satoshi // PLoS ONE;Aug2014, Vol. 9 Issue 8, p1
Royal jelly (RJ) intake lowers serum cholesterol levels in animals and humans, but the active component in RJ that lowers serum cholesterol level and its molecular mechanism are unclear. In this study, we set out to identify the bile acid-binding protein contained in RJ, because dietary bile...
- Low serum cholesterol concentration and serotonin metabolism in men. Steegmans, Paul H.A.; Fekkes, Durk // BMJ: British Medical Journal (International Edition);1/27/96, Vol. 312 Issue 7025, p221
Assesses whether serotonin metabolism is different in subjects with chronically low serum cholesterol concentrations among men in Notterdam, Netherlands. Measuring plasma and platelet serotonin concentrations using a reversed phase high performance liquid chromatography with electrochemical...
- Multidrug Resistance-associated Protein. // Encyclopedic Reference of Cancer;2001, p594
A definition of the term "multidrug resistance-associated protein" is presented. It refers to a member of the ATP-binding cassette superfamily of transporter proteins. It is responsible for the efflux of anionic conjugates of lipophilic compounds from the cell. Many of the substrates are...
- EVALUATION OF A CHOLESTEROL--SYNTHESIS INHIBITOR (TRIPARANOL). Carver, Michael J.; Freeman, John G.; Smith, Jackson A. // Annals of Internal Medicine;Sep60, Vol. 53 Issue 3, p462
Studies the effect of triparanol on the level of serum cholesterol in humans. Changes in total cholesterol; Variations in the levels of serum cholesterol; Effects of dosages of medication on the level of serum cholesterol.
- Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home. Fitzgerald, Michael L.; Moore, Kathryn J.; Freeman, Mason W. // Journal of Molecular Medicine;May2002, Vol. 80 Issue 5, p271
There are many homeostatic mechanisms that contribute to the regulation of cellular and serum cholesterol levels in humans. Much of our understanding of this regulation arose from studies of the cellular pathways controlling cholesterol synthesis and the uptake and degradation of low-density...
- How do I treat case of xanthelasmata? Orteu, Catherine // Pulse;3/3/2003, Vol. 63 Issue 9, p72
Answers a question on how to treat a case of xanthelasmata. Signs and symptoms; Treatment options; Lack of evidence that cholesterol reduction affects the appearance of xanthelasmata.
- Transport of Nucleoside Analogs Across the Plasma Membrane: A Clue to Understanding Drug-Induced Cytotoxicity. Huber-Ruano, I.; Pastor-Anglada, M. // Current Drug Metabolism;May2009, Vol. 10 Issue 4, p347
Nucleoside analogs are widely used in the treatment of cancer and viral-induced diseases. Efficacy of treatments relies upon a variety of events, including transport across tissue and target barriers, which determine drug pharmacokinetics and target cell bioavailability. To exert their action,...