The Spleen in Myelofibrosis With Myeloid Metaplasia

Tefferi, Ayalew; Nagorney, David M.
April 2004
Mayo Clinic Proceedings;Apr2004, Vol. 79 Issue 4, p503
Academic Journal
Presents medical images of the spleen in myelofibrosis with myeloid metaplasia (MMM). Symptoms of progressive splenomegaly in MMM; Spleen-directed management in MMM; Retrospective study of 223 consecutive splenectomies in MMM; Median spleen mass; Observation that splenectomy in MMM does not alter the natural history of the disease but benefits a proportion of patients with the aforementioned spleen-related symptoms.


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