Sleep. 2: pathophysiology of obstructive sleep apnoea/hypopnoea syndrome

Fogel R B; Malhotra A; White D P
February 2004
Thorax;Feb2004, Vol. 59 Issue 2, p159
Academic Journal
The pathogenesis of airway obstruction in patients with obstructive sleep apnoea/hypopnoea syndrome is reviewed. The primary defect is probably an anatomically small or collapsible pharyngeal airway, in combination with a sleep induced fall in upper airway muscle activity.


Related Articles

  • The role of dentistry in the field of sleep medicine...are we respecting the physiology? Cole, Anne-Maree // CRANIO: The Journal of Craniomandibular & Sleep Practice;Jan2014, Vol. 32 Issue 1, p9 

    The author emphasizes the role of dentistry in sleep medicine and in screening for sleep disordered breathing. The author explains the role of dentistry in maintaining a patent airway which is essential to the pathophysiology related to the health consequences of sleep apnea. The author urges...

  • Obstructive sleep apnea and asthma. Salles, Cristina; Terse-Ramos, Regina; Souza-Machado, Adelmir; Cruz, Álvaro A. // Jornal Brasileiro de Pneumologia;sep/out2013, Vol. 39 Issue 5, p604 

    Symptoms of sleep-disordered breathing, especially obstructive sleep apnea syndrome (OSAS), are common in asthma patients and have been associated with asthma severity. It is known that asthma symptoms tend to be more severe at night and that asthma-related deaths are most likely to occur during...

  • Obstructive sleep apnea-hypopnea syndrome: Etiology and diagnosis. Sankri-Tarbichi, Abdul Ghani // Avicenna Journal of Medicine;2012, Vol. 2 Issue 1, p3 

    Sleep disordered breathing is a common chronic condition in the general population. This review will highlight the prevalence of different types of sleep apnea in general and obstructive type in particular in the United States and Middle East. Despite the extensive research studies on the sleep...

  • Polysomnographic Characteristics of Patients with Chronic Insomnia. BaHammam, Ahmed // Sleep & Hypnosis;2004, Vol. 6 Issue 4, p163 

    We conducted this study to assess the usefulness of polysomnography (PSG) in patients referred to the sleep disorders center (SDC) with chronic insomnia. Sixty-seven patients with chronic insomnia who underwent overnight polysomnography were included in the study Clinical diagnoses were reported...

  • A simple procedure for measuring pharyngeal sensitivity: a contribution to the diagnosis of sleep apnoea. Dematteis, M.; LéVy, P.; Pépin, J-L // Thorax;May2005, Vol. 60 Issue 5, p418 

    Background: Patients with severe apnoea may have an impaired pharyngeal dilating reflex related to decreased pharyngeal sensitivity. The accuracy of a simple new procedure to measure pharyngeal sensitivity and to diagnose sleep disordered breathing (5DB) was investigated. Methods: Pharyngeal...

  • The Serbian version of the Epworth Sleepiness Scale. Kopitovic, Ivan; Trajanovic, Nikola; Prodic, Sinisa; Drvenica, Mirjana; Ilic, Miroslav; Kuruc, Vesna; Kojicic, Marija // Sleep & Breathing;Dec2011, Vol. 15 Issue 4, p775 

    Purpose: The Epworth Sleepiness Scale (ESS) is extensively used for evaluating daytime sleepiness in patients with sleep apnea-hypopnea syndrome (SAHS). The aim of this study was to translate and validate the ESS in the Serbian language. Methods: The Serbian version of the ESS (ESSs) was...

  • ETECTION OF REMAINING APNEAS AND HYPOPNEAS UNDER CPAP THERAPY BY AUTOSET SPIRIT COMPARED TO POLYSOMNOGRAPHY. Dahm, C.; Wessendorf, T. E.; Ibrahimova, N.; Moraidis, I.; Teschler, H. // Somnologie;Oct2006 Supplement, Vol. 10, p10 

    The article presents a study which addressed the validity of respiratory events recorded by Autuset Spirit in comparison to the gold standard polysomnography. It cites the uses of continuous positive airway pressure devices. A definition of hypopneas is presented. A set of patients and methods...

  • Apnoea: metabolic and hormonal effects.  // New Zealand Doctor;11/17/2004, p24 

    Discusses the metabolic and hormonal effects of Apnea. Cause of upper airway narrowing during sleep; Effects of large negative swings in intrathoracic pressure caused by further airway narrowing; Anatomical factors that appear to contribute to an abnormal narrowed airway.

  • Correlation between sleep parameters, physical activity and quality of life in somnolent moderate to severe obstructive sleep apnea adult patients. Verwimp, Jelke; Ameye, Lieveke; Bruyneel, Marie // Sleep & Breathing;Sep2013, Vol. 17 Issue 3, p1039 

    Purpose: Several symptoms are described in obstructive sleep apnea (OSA), including excessive daytime sleepiness, depressive mood and neurocognitive dysfunction. However, few studies examined the relationship between objective physical activity, quality of life and sleep parameters. The purpose...


Read the Article


Sign out of this library

Other Topics