TITLE

Cerebral perfusion and stroke

AUTHOR(S)
Markus H S; Markus, H S
PUB. DATE
March 2004
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;Mar2004, Vol. 75 Issue 3, p353
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Stroke is a heterogeneous syndrome caused by multiple disease mechanisms, but all result in a disruption of cerebral blood flow with subsequent tissue damage. This review covers the mechanisms responsible for regulation of the normal cerebral circulation, and how they are disrupted in disease states. A central concept in treating patients with acute ischaemic stroke is the existence of an ischaemic penumbra of potentially salvageable tissue, and the evidence for its existence in humans is reviewed.
ACCESSION #
12653752

 

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