Comments on “The impact of the International Subarachnoid Aneurysm Treatment Trial (ISAT) on neurosurgical practice”

Hernesniemi, Juha; Koivisto, Timo
February 2004
Acta Neurochirurgica;Feb2004, Vol. 146 Issue 2, p203
Academic Journal
The article presents a comment on the impact of the International Subarachnoid Aneurysm Treatment Trial (ISAT) on neurosurgical practice. Endovascular treatment of acutely ruptured intracranial aneurysms with GDC coils is technically feasible in a selected group of patients with the procedure related morbidity and mortality rates equal to those of surgical ligation. However, failure in coil treatment is more common than failure in surgical clipping, and subsequent surgical treatment is frequently required. Surgery provides better primary angiographic occlusion rates in most anterior circulation aneurysms while aneurysms in posterior circulation should be centralized in a few skilled hands due to their small number.


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