Platelet count/spleen diameter ratio predicted the presence of esophageal varices in liver cirrhosis: COMMENTARY

Korula, Jacob
March 2004
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p53
Academic Journal
The article comments on a study conducted to locate the variable that indicate the presence of esophageal varices (EV). The diagnosis of esophageal or gastric varices in patients with cirrhosis confirms the irreversible progression of liver disease and portal hypertension. It also provides opportunities for intervention, including primary prophylaxis for variceal hemorrhage by drugs or endoscopic therapy, future treatment of ascites and hepatic encephalopathy, and consideration for liver transplantation. The study design was sound, having first evaluated the hypothesis in a retrospective study, followed by a prospective study and an analysis of patients with compensated cirrhosis.


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