Platelet count/spleen diameter ratio predicted the presence of esophageal varices in liver cirrhosis

March 2004
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p53
Academic Journal
The article presents a study conducted to locate the clinical, biochemical, and ultrasonographic variables that predict the presence of esophageal varices (EV) in patients with cirrhosis. 266 patients with cirrhosis referred for staging of liver disease were examined. 45 patients were included in the derivation set and 121 in the validation set. Main outcome measures were sensitivity, specificity, and positive and negative likelihood ratios. 61% and 58% of patients in the derivation and validation groups, respectively, had EV. In patients with cirrhosis, platelet count, spleen diameter ratio had 100% sensitivity but specificity varied for predicting the presence of esophageal varices.


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