D-dimer levels < 250 ng/mL after oral anticoagulation predicted a low risk for recurrent venous thromboembolism: COMMENTARY

Kovacs, Michael J.
March 2004
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p50
Academic Journal
The article comments on a study conducted to analyze the association of the levels of D-dimers with the risk of recurrent venous thromboembolism (VTE). Patients with a first episode of unprovoked VTE are at greater risk for recurrence than those who have transient risk factors. The minimum duration of oral anticoagulant therapy (OAT) for such patients is 6 months, but ongoing debate exists about whether indefinite OAT is required. The study adds to the evidence that patients with persistent elevation of D-dimer levels are at greater risk for recurrence than those who have normal D-dimer levels.


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