Dietary supplements containing red clover extracts were no better than placebo for hot flashes in menopause: COMMENTARY

Johnson, Bruce E.
March 2004
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p47
Academic Journal
The article comments on a study conducted to analyze the effect of dietary supplement containing red clover extracts for hot flashes in menopause. The use of estrogen, even to treat hot flashes, has been called into question in light of recent studies. The alternative to estrogen, found in soy and red clover, isoflavones are especially alluring, possessing a chemical structure that allows selective binding to estrogen receptors in a manner similar to that of selective estrogen receptor modulators. The well-designed study assessed the effectiveness of 2 slightly different formulations of isoflavones in treating hot flashes.


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