Oral iron therapy reduced unexplained fatigue in nonanemic women with serum ferritin levels ≤ 50 μg/L

March 2004
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p43
Academic Journal
The article focuses on iron supplementation for unexplained fatigue in non-anemic women. It examines if iron therapy effective for non-anemic women with unexplained fatigue. 144 women 18 to 55 years of age whose primary reason for consulting was fatigue were examined. 75 women were allocated to oral long-acting ferrous sulfate for 4 weeks, and 69 women were allocated to matching placebo. Main outcome was perceived level of fatigue. Secondary outcomes included adherence to treatment. It was concluded that oral iron therapy improved perceived level of fatigue more than did placebo in non-anemic women with unexplained fatigue.


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