TITLE

Review: Prophylactic acetylcysteine reduces contrast nephropathy in chronic renal insufficiency: COMMENTARY

AUTHOR(S)
Buller, Gregory K.
PUB. DATE
March 2004
SOURCE
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p41
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article comments on the study conducted to examine the efficacy of prophylactic acetylcysteine in reducing the incident of contrast nephorpathy in patients with chronic renal insufficiency. Prophylactic use of acetylcysteine, in combination with intravenous saline, has become the standard of care to prevent contrast nephropathy. The study has attempted to better define the efficacy of acetylcysteine, and the meta-analysis showed a benefit associated with its use. The present standard of care should probably include acetylcysteine, 600 mg twice per day, given the day before and the day of the procedure, with intravenous normal saline for several hours before and after radiocontrast administration.
ACCESSION #
12597131

 

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