TITLE

Clarithromycin, lansoprazole, and metronidazole eradicated H. pylori infection in chronic renal insufficiency: COMMENTARY

AUTHOR(S)
Lew, Edward A.
PUB. DATE
March 2004
SOURCE
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p40
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article comments on a study conducted to examine triple therapy for Helicobacter pylori eradication in chronic renal insufficiency. The study compared a metronidazole-clarithromycin-based regimen (CLM) with an amoxicillin-clarithromycin-based regimen (CLA) for eradicating H. pylori in patients with chronic renal insufficiency and dyspepsia. Although the study was well done, 2 points should be noted. First, testing and treating for H. pylori prevents recurrent ulcers in patients with peptic ulcer disease and second that nearly half the study patients had only gastric inflammation on endoscopy, suggesting a diagnosis of nonulcer dyspepsia.
ACCESSION #
12597129

 

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